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IFT122 encodes a member of the WD repeat protein family. Additionally we are shipping Intraflagellar Transport 122 Homolog (Chlamydomonas) Proteins (3) and many more products for this protein.
Showing 10 out of 25 products:
Human Polyclonal IFT122 Primary Antibody for WB - ABIN2785593
Gross, De Baere, Lo, Chang, Messiaen: Cloning and characterization of human WDR10, a novel gene located at 3q21 encoding a WD-repeat protein that is highly expressed in pituitary and testis. in DNA and cell biology 2001
Human Polyclonal IFT122 Primary Antibody for ICC, IF - ABIN4321235
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Polyclonal IFT122 Primary Antibody for ELISA, WB - ABIN565918
Jiang, Chiou, Wang, Chien, Ho, Tsai, Lin, Tsai, Li: Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse. in Human molecular genetics 2009
Data show that IFT122 controls the ciliary localization of Shh (show SHH Antibodies) pathway regulators in different ways.
Studies on a complex A mutant mouse, defective for the Ift122 gene, is reported.
The three patients had different, novel, compound heterozygous mutations in IFT122. Consequently, we compared these three patients to those previously described with IFT122 mutations. Thus, our report serves to add 6 novel mutations to the IFT122 mutation spectrum and to contribute to the IFT122-related clinical characterization.
this study was able to find causative IFT122 mutations in a non-consanguineous family with recurrent abortions.
we found a homozygous missense mutation in the IFT122 (WDR10) gene that cosegregated with Sensenbrenner syndrome
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
intraflagellar transport 122 homolog (Chlamydomonas)
, intraflagellar transport protein 122 homolog
, WD repeat domain 10
, WD repeat-containing protein 10
, intraflagellar transport 122 homolog
, WD repeat-containing protein 140