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anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) Antibodies

The import of proteins into the nucleus is a process that involves at least 2 steps. Additionally we are shipping Karyopherin alpha 1 (Importin alpha 5) Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KPNA1 16646 Q60960
KPNA1 288064  
KPNA1 3836 P52294
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Top anti-Karyopherin alpha 1 (Importin alpha 5) Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-KPNA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-KPNA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... Host: Rabbit  Target Name: KPNA1  Sample Tissue: Jurkat  Antibody Dilu... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185156 staining (1µg/ml) of HeLa lysate (RIPA buffer, 35µg total p... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to KPNA1 on formalin-fixed par... KPNA1 monoclonal antibody (M01), clone 2A4-1B5 Western Blot analysis o... 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB KPNA1 polyclonal antibody (A02), Lot # 061025JCS1 Western Blot analysi... KPNA1 polyclonal antibody (A02), Lot # 061025JCS1. Western Blot analys... 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated DB, WB 50 μg Log in to see 7 to 9 Days
$285.71
Details

KPNA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
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Top referenced anti-Karyopherin alpha 1 (Importin alpha 5) Antibodies

  1. Human Monoclonal KPNA1 Primary Antibody for IHC (p), ELISA - ABIN561614 : Nishimura, Zupunski, Troakes, Kathe, Fratta, Howell, Gallo, Hortobágyi, Shaw, Rogelj: Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration. in Brain : a journal of neurology 2010 (PubMed)
    Show all 3 references for ABIN561614

  2. Cow (Bovine) Polyclonal KPNA1 Primary Antibody for WB - ABIN374391 : Cortes, Ye, Baltimore: RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 2 references for ABIN374391

  3. Human Polyclonal KPNA1 Primary Antibody for ELISA, WB - ABIN561613 : Mahalakshmi, Ng, Guo, Qi, Hunziker, Béguin: Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport. in Traffic (Copenhagen, Denmark) 2007 (PubMed)

  4. Chicken Polyclonal KPNA1 Primary Antibody for WB - ABIN2785822 : Theodore, Kawai, Yang, Kleshchenko, Reddy, Villalta, Arinze: Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. in The Journal of biological chemistry 2008 (PubMed)

  5. Human Polyclonal KPNA1 Primary Antibody for EIA, WB - ABIN783729 : Moroianu: Molecular mechanisms of nuclear protein transport. in Critical reviews in eukaryotic gene expression 1997 (PubMed)

More Antibodies against Karyopherin alpha 1 (Importin alpha 5) Interaction Partners

Mouse (Murine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. mTOR (show FRAP1 Antibodies) and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 (show STAT1 Antibodies) by KPNA1, which are key modulators of STAT1 (show STAT1 Antibodies) expression and apoptosis.

  2. KPNA1 knockdown increased myoblast proliferation.

  3. Importin alpha (show KPNA4 Antibodies) binding and the nuclear import of myopodin (show SYNPO2 Antibodies) are regulated by the serine/threonine phosphorylation-dependent binding of myopodin (show SYNPO2 Antibodies) to 14-3-3 (show YWHAQ Antibodies). These results establish a novel paradigm for the promotion of nuclear import by 14-3-3 (show YWHAQ Antibodies) binding.

  4. PTH1R (show PTH1R Antibodies) forms a complex with the transport regulatory proteins, importin alpha(1) and importin beta (show KPNB1 Antibodies), and nuclear PTH1R (show PTH1R Antibodies) is associated with the nucleoplasm

  5. Here, we show that the expression of importin-alpha (show KPNA4 Antibodies) subtypes is strictly regulated during neural differentiation of mouse embryonic stem (ES) cells, and that the switching of importin-alpha (show KPNA4 Antibodies) subtype expression is critical for neural differentiation.

  6. Absence of importin (show KPNA4 Antibodies) a5 during mouse development does not significantly interfere with neuronal differentiation and brain development.

Human Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Data show that cytoskeleton associated protein 5 (chTOG (show CKAP5 Antibodies)) only weakly promotes importin (show KPNA4 Antibodies)-regulated microtubule nucleation, but acts synergistically with TPX2 (show TPX2 Antibodies) protein.

  2. BIG3 (show WDR5 Antibodies) may block the KPNAs (KPNA1, KPNA5 (show KPNA5 Antibodies), and KPNA6 (show KPNA6 Antibodies)) binding region(s) of PHB2 (show PHB2 Antibodies).

  3. miR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin alpha4 and alpha5 in IgA nephropathy

  4. Bel1 fragment with residues 215-223, which bears the NLS (show ALDH1A2 Antibodies), interacts with KPNA1, KPNA6 (show KPNA6 Antibodies), and KPNA7 (show KPNA6 Antibodies).

  5. Results indicate CTNNBL1 (show CTNNBL1 Antibodies) as a unique selective nuclear localization signals (NLSs)-binding protein with striking differences from karyopherin-alphas.

  6. This supports the notion that de novo mutations KPNA1 in are extremely rare in schizophrenia

  7. LRRC59 facilitates transport of cytosolic FGF1 through nuclear pores by interaction with Kpns and movement of LRRC59 along the ER and NE membranes

  8. mTOR (show FRAP1 Antibodies) and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 (show STAT1 Antibodies) by KPNA1, which are key modulators of STAT1 (show STAT1 Antibodies) expression and apoptosis.

  9. the requirement for and the regulation of CAS (show CSE1L Antibodies) in the functioning of the Vpr-Impalpha complex

  10. Nucleoporin Nup50 (show NUP50 Antibodies) stabilizes closed conformation of armadillo (show PKP1 Antibodies) repeat 10 in importin (show KPNA4 Antibodies) alpha5.

Pig (Porcine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Nsp1beta inhibits interferon-activated (show MNDA Antibodies) STAT1 (show STAT1 Antibodies)/STAT2 (show STAT2 Antibodies) signal transduction by inducing karyopherin-alpha1 degradation.

Cow (Bovine) Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Bovine ephemeral fever rhabdovirus alpha1 protein binds bovin importin (show KPNA4 Antibodies) beta1 and importin 7 (show IPO7 Antibodies).

Xenopus laevis Karyopherin alpha 1 (Importin alpha 5) (KPNA1) interaction partners

  1. Data show that either an excess or a lack of importin alpha (show KPNA4 Antibodies) blocks nuclear envelope (NE) assembly in vitro, and that it also functions in NE assembly in conjunction with nuclear localization signal-containing partner proteins.

Karyopherin alpha 1 (Importin alpha 5) (KPNA1) Antigen Profile

Protein Summary

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KPNA1

  • importin alpha-1 subunit (EHI_124900) antibody
  • karyopherin alpha 1 (importin alpha 5) (KPNA1) antibody
  • karyopherin (importin) alpha 1 (Kpna1) antibody
  • karyopherin alpha 1 (Kpna1) antibody
  • karyopherin alpha 1 (importin alpha 5) (kpna1) antibody
  • karyopherin alpha 7 (importin alpha 8) (kpna7) antibody
  • AW494490 antibody
  • IPOA5 antibody
  • kpna1 antibody
  • mSRP1 antibody
  • NPI-1 antibody
  • NPI1 antibody
  • RCH2 antibody
  • si:ch211-161h7.7 antibody
  • SRP1 antibody

Protein level used designations for KPNA1

importin alpha-1 subunit , Importin subunit alpha-1 , importin subunit alpha-5 , karyopherin subunit alpha-1 , NPI-1 , RAG cohort protein 2 , SRP1-beta , importin alpha-S1 , importin subunit alpha-1 , m-importin-alpha-S1 , nucleoprotein interactor 1 , importin alpha 5 , importin alpha-5 , karyopherin (importin) alpha 1 , karyopherin/importin alpha-1 , importin-alpha-S1 , recombination activating gene cohort 2 , importin alpha 1a

GENE ID SPECIES
6220066 Entamoeba histolytica HM-1:IMSS
100172964 Pongo abelii
16646 Mus musculus
288064 Rattus norvegicus
3836 Homo sapiens
478585 Canis lupus familiaris
397235 Sus scrofa
539679 Bos taurus
572542 Danio rerio
418271 Gallus gallus
398026 Xenopus laevis
Selected quality suppliers for anti-Karyopherin alpha 1 (Importin alpha 5) (KPNA1) Antibodies
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