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KPNA1 antibody (AA 1-300)

KPNA1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3022472
  • Target See all KPNA1 Antibodies
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    Binding Specificity
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 1-300
    Reactivity
    • 36
    • 18
    • 17
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 26
    • 8
    • 1
    • 1
    Rabbit
    Clonality
    • 30
    • 6
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA1 antibody is un-conjugated
    Application
    • 25
    • 14
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MTTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE VMSDGGFHEA QISNMEMAPG GVITSDMIEM IFSKSPEQQL SATQKFRKLL SKEPNPPIDE VISTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRIVIQAGA VPIFIELLSS EFEDVQEQAV WALGNIAGDS TMCRDYVLDC NILPPLLQLF SKQNRLTMTR NAVWALSNLC RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KPNA1 (NP_002255.3).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

  • Target
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    Alternative Name
    KPNA1 (KPNA1 Products)
    Synonyms
    IPOA5 antibody, NPI-1 antibody, RCH2 antibody, SRP1 antibody, AW494490 antibody, NPI1 antibody, Rch2 antibody, mSRP1 antibody, si:ch211-161h7.7 antibody, karyopherin subunit alpha 1 antibody, importin alpha-1 subunit antibody, karyopherin (importin) alpha 1 antibody, karyopherin alpha 1 (importin alpha 5) antibody, KPNA1 antibody, Kpna1 antibody, EHI_124900 antibody, kpna1 antibody
    Background
    The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.,KPNA1,IPOA5,NPI-1,RCH2,SRP1,Signal Transduction,Immunology & Inflammation,KPNA1
    Molecular Weight
    60 kDa
    Gene ID
    3836
    UniProt
    P52294
    Pathways
    M Phase, Protein targeting to Nucleus
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