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Karyopherin alpha 4 (Importin alpha 3) Proteins (KPNA4)

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Additionally we are shipping KPNA4 Antibodies (78) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KPNA4 16649 O35343
KPNA4 3840 O00629
Rat KPNA4 KPNA4 361959  
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Top KPNA4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KPNA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Karyopherin alpha 4 (Importin alpha 3) (KPNA4) Interaction Partners

Fruit Fly (Drosophila melanogaster) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Expression of DnaJ-1 (show DNAJB1 Proteins) potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 also leads to reduced toxicity from pathogenic CACNA1A (show CACNA1A Proteins)

  2. These results reveal that the nuclear transport of Notch (show NOTCH1 Proteins) intracellular domain (Notch (show NOTCH1 Proteins)-ICD)is mediated by the canonical Importin-alpha3/Importin-beta (show KPNB1 Proteins) transport pathway.

  3. each Imp (show BRAP Proteins)-alpha protein carries during Drosophila spermatogenesis distinct, albeit overlapping, functions that may involve nuclear import of proteins, microtubule organisation, and other yet unknown processes

  4. Data show that Drosophila Naked cuticle (Nkd (show NKD1 Proteins)) engages the nuclear import adaptor Importin-alpha3 to antagonize Wnt (show WNT4 Proteins)/beta-catenin signaling.

Arabidopsis thaliana Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. MOS6, identified by positional cloning, encodes importin alpha3, one of eight alpha importins in Arabidopsis [MOS6]

Mouse (Murine) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Our results showed that miR (show MLXIP Proteins)-181 family expression was closely correlated with TCGA subtypes and patients' overall survival, indicating that miR (show MLXIP Proteins)-181b.

  2. Loss of importin alpha 4 is associated with oxidative stress.

  3. IMPalpha4 overexpression induced a significant decrease in Oct3/4 (show POU5F1 Proteins) protein levels compared to control transfections. IMPalpha4 protein showed a unique and striking shift in subcellular localization from the nucleus to the cytoplasm during differentiation.

  4. Expression of importin alpha3, a protein involved in p50 (show LSP1 Proteins)/p65 (show NFkBP65 Proteins) nuclear import, was decreased in colonic mucosa cells of (show PHB Proteins)transgenic mice overexpressing human prohibitin.

  5. In postnatal testes, importin alpha3 and alpha4 in spermatocytes, spermatids, and Sertoli cells display cytoplasmic and nuclear localization, respectively.

Cow (Bovine) Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. These results suggest that the bovine adenovirus-3 52K protein contains a bipartite nuclear localization signal, which preferentially utilize an importin alpha3 nuclear import receptor-mediated pathway to transport the 52K protein to the nucleus.

Human Karyopherin alpha 4 (Importin alpha 3) (KPNA4) interaction partners

  1. Our results showed that miR (show MLXIP Proteins)-181 family expression was closely correlated with TCGA subtypes and patients' overall survival, indicating that miR (show MLXIP Proteins)-181b.

  2. Karyopherin alpha 3 and karyopherin alpha 4 proteins mediate the nuclear import of methyl-CpG binding protein 2.

  3. miR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin alpha4 and alpha5 in IgA nephropathy

  4. upon DNA damage transport adaptor importin-alpha4 imports XPA into the nucleus in an ATR-dependent manner.

  5. Importin alpha3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function.

  6. Impalpha3 is an HIV integrase-interacting cofactor and is required for efficient HIV-1 nuclear import and replication.

  7. stress-induced accumulation of non-ubiquitinated p53 (show TP53 Proteins) in the cytoplasm promotes interaction with importin-alpha3 and rapid import

  8. Expression of importin alpha3, a protein involved in p50 (show CD40 Proteins)/p65 (show GORASP1 Proteins) nuclear import, was decreased in cells overexpressing PHB (show PHB Proteins).

  9. Our results indicate that the nuclear import of RHA is mediated by the importin-alpha3/importin-beta (show KPNB1 Proteins)-dependent pathway and suggest that the specificity for importin may regulate the functions of cargo proteins.

  10. Daxx (show DAXX Proteins) interacts selectively with importin alpha3 through its NLS1 and NLS2 sequences. Conversely, importin alpha3 utilizes two NLS (show ALDH1A2 Proteins)-binding sites for Daxx (show DAXX Proteins) interaction, suggesting that it mediates nuclear import of Daxx (show DAXX Proteins).

KPNA4 Protein Profile

Protein Summary

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Gene names and symbols associated with KPNA4

  • karyopherin alpha3 (Kap-alpha3)
  • Importin alpha 3 (MOS6)
  • importin alpha 3 (LOC100533341)
  • karyopherin alpha 4 (importin alpha 3) (LOC100224013)
  • karyopherin (importin) alpha 4 (Kpna4)
  • karyopherin alpha 4 (importin alpha 3) (KPNA4)
  • karyopherin alpha 4 (importin alpha 3) (Kpna4)
  • karyopherin alpha 4 (importin alpha 3) (kpna4)
  • 6 protein
  • 0335/13 protein
  • 1110058D08Rik protein
  • alphaKap3 protein
  • ATIMPALPHA3 protein
  • CG9423 protein
  • Dalpha3 protein
  • dimpalpha3 protein
  • dKap-alpha3 protein
  • Dmel\\CG9423 protein
  • imp-a3 protein
  • imp-alpha3 protein
  • IMPA-3 protein
  • Imp alpha-3 protein
  • impalpha3 protein
  • imp alpha3 protein
  • importin protein
  • IMPORTIN ALPHA 3 protein
  • IMPORTIN ALPHA ISOFORM 3 protein
  • ipoa3 protein
  • Kap-?3 protein
  • KAP-ALPHA3 protein
  • Kapalpha3 protein
  • Kap alpha3 protein
  • Kpna3 protein
  • l(3)S033513 protein
  • LOC100224013 protein
  • MODIFIER OF SNC1 protein
  • qip1 protein
  • srp3 protein
  • T10M13.16 protein
  • T10M13_16 protein

Protein level used designations for KPNA4

CG9423-PA , CG9423-PB , CG9423-PC , CG9423-PD , Importin-alpha3 , Kap-alpha3-PA , Kap-alpha3-PB , Kap-alpha3-PC , Kap-alpha3-PD , dImportin-alpha3 , importin a3 , importin alpha , importin alpha-3 , importin alpha3 , karyopherin a3 , karyopherin alpha4 , karyopherin-alpha3 , karyopherin-alpha4 , importin alpha 3 , karyopherin alpha 4 (importin alpha 3) , importin alpha Q1 , importin subunit alpha-3 , importin subunit alpha-4 , karyopherin subunit alpha-4 , qip1 , karyopherin (importin) alpha 4 , predicted role in nuclear import

GENE ID SPECIES
41158 Drosophila melanogaster
827472 Arabidopsis thaliana
100533341 Aplysia californica
100224013 Taeniopygia guttata
16649 Mus musculus
535090 Bos taurus
3840 Homo sapiens
478680 Canis lupus familiaris
361959 Rattus norvegicus
432010 Xenopus laevis
425012 Gallus gallus
Selected quality suppliers for KPNA4 Proteins (KPNA4)
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