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Keratin 5 Proteins (KRT5)

The protein encoded by KRT5 is a member of the keratin gene family. Additionally we are shipping Keratin 5 Antibodies (239) and Keratin 5 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KRT5 3852 P13647
KRT5 110308 Q922U2
KRT5 369017 Q6P6Q2
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Top Keratin 5 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag   50 μg Log in to see 9 to 11 Days
$418.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,429.17
Details
HOST_Escherichia coli (E. coli) Rat His tag,S tag   100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$794.65
Details

KRT5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Keratin 5 (KRT5) Interaction Partners

Zebrafish Keratin 5 (KRT5) interaction partners

  1. data show that a cis (show CISH Proteins)-element of the DNA segment in the CKII gene is required for epidermal cell-specific expression of CKII and that a minimal region upstream of the transcription start site is required for this expression restricted to epidermal cells

Human Keratin 5 (KRT5) interaction partners

  1. identification of 29 different mutations in KRT5 and KRT14 (show KRT14 Proteins), 11 of which were novel, in a Polish cohort of epidermolysis bullosa simplex patients

  2. KRT5 protein mutation may predispose to a severe lethal variant of epidermolysis bullosa simplex.

  3. study showed that 34betaE12 is the most appropriate negative marker to combine with alpha-methylacyl coenzyme A racemase (show AMACR Proteins) as a positive marker for the diagnosis of prostate adenocarcinoma[34betaE12]

  4. Different staining patterns can be seen with CK5/6 and p63 (show RPE65 Proteins); however, if they are used together with TTF-1 (show NKX2-1 Proteins) they can be used in subtyping lung neoplasms.

  5. CK5/6 have roles in biologically aggressive tumors likely to display resistance to trastuzumab ab initio in women diagnosed with HER2 (show ERBB2 Proteins)+ cancer

  6. Keratinocytes adhesion and stiffness depends on KRT5 protein missense mutation.

  7. There were differences between CK5/6, p63 (show RPE65 Proteins),CK34betaE12 and TTF-1 (show NKX2-1 Proteins) expression with tumor differentiation in squamous cell carcinoma or adenocarcinomas

  8. in silico analysis of all epidermolysis bullosa simplex causing point mutations on the 2B domain of K5 and K14 (show KRT14 Proteins); result showed all pathogenic point mutations exert their dominant negative effect on the K5/K14 (show KRT14 Proteins) coiled-coil heterodimer complex by altering interchain interaction,leading to changes in stability and assembly competence of the heterodimer complex

  9. CK5/6, IMP3 (show IGF2BP3 Proteins) and TTF1 (show NKX2-1 Proteins) immunostaining appears to be useful to improve the accuracy of cytological diagnoses between reactive mesothelial cells, metastatic adenocarcinoma of lung and non-lung origin in pleural effusion.

  10. immunoreactivity cytokeratin 5 and CD44 (show CD44 Proteins) commonly immunostained Nested/microcystic urothelial carcinoma (US) and some invasive high grade UC

Cow (Bovine) Keratin 5 (KRT5) interaction partners

  1. NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5-Cre transgenic mice.

Mouse (Murine) Keratin 5 (KRT5) interaction partners

  1. Directed expression of a chimeric type II keratin (show KRT80 Proteins) partially rescues keratin 5 (show KRT36 Proteins)-null mice.

  2. NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5 (show KRT36 Proteins)-Cre transgenic mice.

  3. Mice lacking the prostate epithelial AR have increased apoptosis in epithelial CK8 (show KRT8 Proteins)-positive luminal cells and increased proliferation in epithelial CK5-positive basal cells.

  4. The involvement of Hsc70 and Hsp70 in mutant keratin degradation was demonstrated using CHIP-p.Met1_Ala142del (DeltaTPR-CHIP).

  5. p63 (show CKAP4 Proteins) protein is essential for the embryonic development of vibrissae and teeth; while it localizes with K5 in vibrissae, it is not fully colocalized with nuclear Ki67 (show MKI67 Proteins) expression

  6. keratin 5 (show KRT36 Proteins) mutations contribute to epidermolysis bullosa simplex in a mouse model by inducing local inflammation that mediates a stress response

  7. DeltaNp63 alone can restore the expression of the basal keratins and reinitiate the failed epidermal differentiation program in the skin of p63 (show CKAP4 Proteins) null animals.

Keratin 5 (KRT5) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene names and symbols associated with Keratin 5 Proteins (KRT5)

  • keratin 71 (KRT71)
  • keratin 5 (krt5)
  • keratin 5 (KRT5)
  • keratin 5 (Krt5)
  • 3300001P10Rik protein
  • AW146334 protein
  • CK-5 protein
  • CK5 protein
  • ckii protein
  • DDD protein
  • DDD1 protein
  • EBS2 protein
  • K5 protein
  • Keratin-5 protein
  • Krt2-5 protein
  • KRT5A protein
  • KRT75 protein
  • Sak57 protein
  • Tfip8 protein
  • wu:fb02h09 protein
  • wu:fj02d02 protein
  • wu:fk78b12 protein
  • zfCKII protein

Protein level used designations for Keratin 5 Proteins (KRT5)

keratin, type II cytoskeletal 71 , type II cytokeratin , keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) , keratin 75 , keratin, type II cytoskeletal 5 , type II alpha keratin IIA , 58 kda cytokeratin , CK-5 , cytokeratin-5 , epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types , type-II keratin Kb5 , K5 , keratin, type II cytoskeletal 60 kDa, component III , keratin-5 , 58 kDa cytokeratin , cytokeratin 5 , keratin complex 2, basic, gene 5 , tuftelin interacting protein 8 , keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types) , Cytokeratin-5 , Type-II keratin Kb5

GENE ID SPECIES
486522 Canis lupus familiaris
797351 Danio rerio
407779 Gallus gallus
3852 Homo sapiens
281268 Bos taurus
110308 Mus musculus
369017 Rattus norvegicus
100615215 Pan troglodytes
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