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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) Antibodies

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Proteins (17) and Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KLRK1 22914 P26718
KLRK1 27007 O54709
KLRK1 24934 O70215
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Top anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Antibodies at antibodies-online.com

Showing 10 out of 167 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IHC (fro), IP Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN C... 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185435 staining (0.3µg/ml) of human spleen lysate (RIPA buffer, 35... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human nasopharyngeal carcinoma la... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse FITC FACS   25 μg Log in to see 6 to 8 Days
$198.00
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated Func, FACS, IHC (fro), IP   0.5 mg Log in to see 6 to 8 Days
$632.50
Details
Mouse Hamster FITC BR, FACS, IHC, WB 50 μg Log in to see 10 to 12 Days
$97.84
Details
Mouse Armenian Hamster Un-conjugated Func, FACS Surface staining of mouse splenocytes with anti-mouse NKG2D (A10) PE a... 100 μg Log in to see 5 to 6 Days
$198.82
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$275.00
Details

KLRK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Antibodies

  1. Mouse (Murine) Monoclonal KLRK1 Primary Antibody for BR, FACS - ABIN2661982 : Gilfillan, Ho, Cella, Yokoyama, Colonna: NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. in Nature immunology 2002 (PubMed)
    Show all 10 references for ABIN2661982

  2. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN120295 : Bauer, Groh, Wu, Steinle, Phillips, Lanier, Spies: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 6 references for ABIN120295

  3. Human Monoclonal KLRK1 Primary Antibody for Func, FACS - ABIN120293 : Groh, Bruhl, El-Gabalawy, Nelson, Spies: Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 6 references for ABIN120293

  4. Human Monoclonal KLRK1 Primary Antibody for FACS, IHC (fro) - ABIN120294 : Wu, Song, Bakker, Bauer, Spies, Lanier, Phillips: An activating immunoreceptor complex formed by NKG2D and DAP10. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 6 references for ABIN120294

  5. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN320264 : Das, Sugita, Brenner: Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 6 references for ABIN320264

  6. Human Polyclonal KLRK1 Primary Antibody for IF (p), IHC (p) - ABIN730078 : Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers. in Archivum immunologiae et therapiae experimentalis 2014 (PubMed)
    Show all 3 references for ABIN730078

  7. Human Polyclonal KLRK1 Primary Antibody for ELISA, WB - ABIN185435 : Hayakawa, Smyth: Innate immune recognition and suppression of tumors. in Advances in cancer research 2006 (PubMed)
    Show all 2 references for ABIN185435

  8. Human Polyclonal KLRK1 Primary Antibody for ELISA, WB - ABIN1452156 : Glienke, Sobanov, Brostjan, Steffens, Nguyen, Lehrach, Hofer, Francis: The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex. in Immunogenetics 1998 (PubMed)

  9. Mouse (Murine) Monoclonal KLRK1 Primary Antibody for Func, FACS - ABIN282396 : Ho, Carayannopoulos, Poursine-Laurent, Kinder, Plougastel, Smith, Yokoyama: Costimulation of multiple NK cell activation receptors by NKG2D. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)

More Antibodies against Killer Cell Lectin-Like Receptor Subfamily K, Member 1 Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. The reduced cell surface expression of NKG2D in response to engagement by MICA (show MICA Antibodies)-129Met variants appeared to reduce the severity of acute graft-versus-host disease.

  2. Bispecific protein rG7S-MICA (show MICA Antibodies) recruits natural killer cells and enhances NKG2D-mediated immunosurveillance against hepatocellular carcinoma.

  3. Taken together, these results demonstrate that endogenous levels of IFN-alpha (show IFNA Antibodies) secreted by plasmacytoid dendritic cells induce natural killer cells to lyse HIV-1-infected autologous CD4 (show CD4 Antibodies)+ primary T cells via the engagement of NKp46 (show NCR1 Antibodies) and NKG2D.

  4. these findings suggest that TGFbetainduced release of soluble MICA (show MICA Antibodies) leads to downregulation of NKG2D, thereby preventing NK cellmediated cytotoxicity toward renal proximal tubular epithelial cells in renal IRI

  5. In conclusion DNT (show NT5C Antibodies) cell can significantly inhibit the growth of pancreatic carcinoma in vivo, and the mechanism may be involved in abnormal expressions of MICA (show MICA Antibodies) and NKG2D.

  6. study indicates a direct NKG2D-dependent stimulatory effect of human CD34+ cells on allogeneic NK cells. These findings may be relevant to the NK-mediated rejection effect in HLA-mismatched hematopoietic stem cell transplantation

  7. Both mRNA and protein levels of NKG2D, MICA (show MICA Antibodies), MICB (show MICB Antibodies) and ULBP were upregulated in six types of thymomas compared with those in atrophic thymus or proliferating thymus.

  8. GSK-3 (show GSK3b Antibodies) undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D and 2B4 (show CD244 Antibodies), either individually or in combination.

  9. NKG2D signaling leads to NK cell mediated lysis of childhood AML (show RUNX1 Antibodies) despite high HLA I expression.

  10. There was a significant association between congenital cytomegalovirus disease and a single nucleotide polymorphism, Thr72Ala, in NKG2D.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. These results support the conclusion that svH1C mimics Neu5Ac-containing sequences and interacts with cell-surface receptor NKG2D, which contains a lectin-like domain

  2. These results indicate that, unlike in the pancreas, NKG2D-NKG2D ligand interaction does not play a critical role in obesity-induced inflammation in the adipose tissue.

  3. The results show that NK cells and the NKG2D receptor play a role in control of lymphomas, and that selection of NKG2D-ligand (MULT1 (show ULBP1 Antibodies)) loss mutants provides a mechanism for tumor escape.

  4. these data support a novel role for NKG2D expression by CD8 (show CD8A Antibodies)(+) T cells during allogeneic HSCT, which could be potentially therapeutically exploited to separate GVHD from GVT effects.

  5. NKG2D and NKG2DL are involved in allergen-induced activation of dendritic epidermal T cells and the NKG2D/NKG2DL pathway might be a potential target for treatment of contact hypersensitivity.

  6. Viral infection of cultured cells increased RAE-1 (show RAE1 Antibodies) expression, resulting in enhanced NK cell-mediated killing through NKG2D recognition.

  7. Activation through the NKG2D receptor leads to the differential activation of the NF-kappaB (show NFKB1 Antibodies) signaling pathway and potentially enhances the anti-tumor and anti-viral functions of effector CD8 (show CD8A Antibodies)(+) T cells.

  8. Desiccating stress-induced chemokine (show CCL1 Antibodies) expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 (show RAE1 Antibodies) and release of IFN-gamma (show IFNG Antibodies) in experimental dry eye.

  9. Highly target-specific liver NKT (show CTSL1 Antibodies) cells selectively remove activated hepatic stellate cells through an NKG2D-Rae1 (show RAE1 Antibodies) interaction to ameliorate liver fibrosis after IL-30 treatment.

  10. a protective role of NKG2D-activated natural killer cells in coxsackievirus B3 myocarditis leading to an effective virus clearance

Pig (Porcine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. The effect of Bacillus cereus on the stress response of enterocytes, including the expression of NKG2D, is reported.

Rhesus Monkey Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. Determined expressions of NKG2D in decidual natural killer cells in patients having spontaneous abortions.

Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) Antigen Profile

Protein Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.

Gene names and symbols associated with KLRK1

  • killer cell lectin-like receptor subfamily K, member 1 (KLRK1) antibody
  • NKG2-D type II integral membrane protein-like (LOC100398970) antibody
  • killer cell lectin-like receptor subfamily K, member 1 (Klrk1) antibody
  • NKG2D protein (NKG2D) antibody
  • CD314 antibody
  • D6H12S2489E antibody
  • D12S2489E antibody
  • KLR antibody
  • KLRK1 antibody
  • NKG2-D antibody
  • Nkg2d antibody
  • Nkrp2 antibody

Protein level used designations for KLRK1

killer cell lectin-like receptor subfamily K, member 1 , NKG2-D type II integral membrane protein-like , NK cell receptor D , NKG2-D type II integral membrane protein , NKG2-D-activating NK receptor , natural killer cell group 2D , NK lectin-like receptor , NKLLR , NKR-P2, ortholog of human NKG2D , killer cell lectin-like receptor subfamily K member 1 , NKG2-D activating NK receptor

GENE ID SPECIES
611355 Canis lupus familiaris
100126736 Papio anubis
100398970 Callithrix jacchus
22914 Homo sapiens
27007 Mus musculus
24934 Rattus norvegicus
396737 Sus scrofa
450153 Pan troglodytes
574240 Macaca mulatta
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