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Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) Proteins (KMO)

KMO encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Additionally we are shipping KMO Antibodies (54) and KMO Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KMO 98256 Q91WN4
Rat KMO KMO 59113 O88867
KMO 8564 O15229
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Top KMO Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
Yeast Myxococcus His tag   1 mg Log in to see 56 to 66 Days
$3,305.50
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KMO Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , , ,
, , ,

More Proteins for Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) Interaction Partners

Mouse (Murine) Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) interaction partners

  1. Mice lacking the enzyme kynurenine-3-monoxygenase (KMO) also showed no changes in hippocampal expression of several of these proteins or the 70-kDa and 100-kDa variants of Disrupted in Schizophrenia-1 (DISC1 (show DISC1 Proteins)).

  2. KMO KO mice have a robust biochemical phenotype that protects against extrapancreatic tissue injury to the lung, kidney and liver in experimental acute pancreatitis-multiple organ dysfunction syndrome.

  3. KMO knockout mice have alterations in the levels of several tryptophan metabolites.

  4. expression of KMO by Th17 cells serves to limit their continuous exposure to physiological levels of endogenous aryl hydrocarbon receptor (show AHR Proteins) ligands in vivo.

  5. partial protection against cerebral malaria was observed in C57BL/6 mice treated with Ro 61-8048, an inhibitor of kynurenine-3-hydroxylase. Protection was associated with suppressed levels of picolinic acid within the brain.

Human Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) interaction partners

  1. These results suggest that KMO exhibits tumor-promoting effects towards hepatocellular carcinoma (HCC (show FAM126A Proteins)) and it may serve as a novel prognostic marker in HCC (show FAM126A Proteins).

  2. Results suggest that KMO variation influences a range of cognitive domains known to predict functional outcome in schizophrenia

  3. Two KMO SNPs were observed more often in schizophrenia patient group compared with healthy controls.

  4. findings from five independent cohorts suggest that genetic variation in KMO influences the risk for psychotic features in mania of bipolar disorder patients.

  5. Study reporting on the first successful bacterial (Escherichia coli) expression of active FLAGtrade mark-tagged human KMO enzyme expressed in the soluble fraction and progress towards its purification.

  6. analyzed association between KMO gene polymorphisms and CSF (show CSF2 Proteins) concentrations of kynurenic acid in patients with schizophrenia and controls. results suggest that the nonsynonymous KMO SNP rs1053230 influences CSF (show CSF2 Proteins) concentrations of KYNA.

  7. the function KMO AND indoleamine 2,3-dioxygenase may change from a role in immunosuppression at the maternal-fetal interface in early pregnancy, to one associated with regulation of fetoplacental blood flow or placental metabolism in late gestation

  8. Results suggest that kynurenine 3-monooxygenase is unlikely to be related to the development of schizophrenia in Japanese.

Pig (Porcine) Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) interaction partners

  1. The carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase plays a dual role as a mitochondrial-targeting signal and an enzyme.

KMO Protein Profile

Protein Summary

This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.

Gene names and symbols associated with KMO

  • kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo)
  • kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO)
  • AI046660 protein
  • dJ317G22.1 protein

Protein level used designations for KMO

kynurenine 3-hydroxylase , kynurenine 3-monooxygenase , L-kynurenine 3-monooxygenase Fpk , fpk

GENE ID SPECIES
98256 Mus musculus
59113 Rattus norvegicus
8564 Homo sapiens
397148 Sus scrofa
Selected quality suppliers for KMO Proteins (KMO)
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