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LIM Domain Binding 1 Proteins (LDB1)

Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. Additionally we are shipping LIM Domain Binding 1 Protein Antibodies (74) and LIM Domain Binding 1 Protein Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LDB1 16825 P70662
LDB1 8861 Q86U70
Rat LDB1 LDB1 309447  
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Top LIM Domain Binding 1 Protein Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,023.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,030.50
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,142.33
Details

LDB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for LIM Domain Binding 1 (LDB1) Interaction Partners

Xenopus laevis LIM Domain Binding 1 (LDB1) interaction partners

  1. The functional cloning, expression pattern, overexpression, and knockdown data show that an ldb1-regulated mechanism acts as an early signal for Xenopus lens induction.

Mouse (Murine) LIM Domain Binding 1 (LDB1) interaction partners

  1. SSBP3 (show SSBP3 Proteins) Interacts With Islet-1 (show ISL1 Proteins) and Ldb1 to Impact Pancreatic beta-Cell Target Genes

  2. the Isl1 (show ISL1 Proteins)/Ldb1 complex orchestrates a network for heart-specific transcriptional regulation and coordination in three-dimensional space during cardiogenesis.

  3. results indicate that LDB1-dependent looping events can deliver repressive cargo to cognate promoters to mediate promoter pausing events in a pituitary cell type

  4. Expression pattern of Isl1 (show ISL1 Proteins) and its co-factor Ldb1, were analyzed in small intestine.

  5. Data suggest that the function of LIM domain binding protein 1 (LDB1) in the neural crest-derived palatal mesenchyme is essential for normal morphogenesis of the secondary palate.

  6. the LDB1 dimerization domain (DD) is necessary and, when fused to LMO2 (show LMO2 Proteins), sufficient to completely restore LCR (show CBR2 Proteins)-promoter looping and transcription in LDB1-depleted cells

  7. Ldb1 plays an essential role as a transcription co-regulator of Lhx6 (show LHX6 Proteins) and Lhx8 (show LHX8 Proteins) in the control of mammalian telencephalon development.

  8. These results provide a foundation for defining the mechanism and scope of Ldb1 complex activity during erythropoiesis.

  9. Data indicte that the regulation of essential developmental factors by Ldb1 defines it as an upstream transcriptional regulator of hematopoietic/endothelial development.

  10. Isl1 (show ISL1 Proteins) and the Ldb co-regulators of transcription are essential early determinants of mouse limb development

Human LIM Domain Binding 1 (LDB1) interaction partners

  1. SSBP3 (show SSBP3 Proteins) Interacts With Islet-1 (show ISL1 Proteins) and Ldb1 to Impact Pancreatic beta-Cell Target Genes

  2. Alanine scanning mutagenesis of the LIM (show PDLIM5 Proteins) interaction domain of LDB1 revealed a discrete motif, R(320)LITR, required for LMO2 (show LMO2 Proteins) binding.

  3. Clim2, in a complex with LMO4 (show LMO4 Proteins), supports mammary stem cells by directly targeting the Fgfr2 (show FGFR2 Proteins) promoter in basal cells to increase its expression

  4. In t(8;21) leukemia cells, LDB1 functions as a component of the stable AML1 (show RUNX1 Proteins)-ETO (show RUNX1T1 Proteins)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  5. We investigated NLI (Ldb1 homolog) complex occupancy and chromatin conformation of the beta-globin (show HBB Proteins) locus in human erythroid cells.

  6. These studies are consistent with a model in which TIF1gamma (show TRIM33 Proteins) acts to ubiquitinate LDB1 leading to degradation of LDB1 and changes in transcription of LDB1-dependent promoters.

  7. Expression of LDB1 (LIM-domain-binding 1) protein in which Lys134 is replaced with arginine leads to enhanced expression of the mutant protein compared with the wild-type protein.

  8. 1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4 (show LMO4 Proteins):ldb1 complex

  9. Ssdp (show SSBP3 Proteins) proteins interact with the LIM (show PDLIM5 Proteins)-domain-binding protein Ldb1 to regulate development

  10. characterize the assembly of a five-component complex containing TAL1 (show TAL1 Proteins), LMO2 (show LMO2 Proteins), Ldb1, E12 (show ELSPBP1 Proteins), and DNA. The bHLH domains of TAL1 (show TAL1 Proteins) and E12 (show ELSPBP1 Proteins) alone primarily formed helical homodimers, but together formed heterodimers, to which LMO2 (show LMO2 Proteins) bound with high affinity

Zebrafish LIM Domain Binding 1 (LDB1) interaction partners

  1. Centrosome movements in vivo correlate with specific neurite formation downstream of LIM homeodomain transcription factor activity.

  2. Study identifies a number of novel Ldb1 interacting proteins in murine erythroleukaemic cells, namely Eto-2 (show CBFA2T3 Proteins), the cyclin-dependent kinase (show CDK1 Proteins) Cdk9 (show CDK9 Proteins), Lmo4 (show LMO4 Proteins); morphilino-mediated knockdowns in zebrafish show these factors to be essential for haematopoiesis.

LIM Domain Binding 1 Protein (LDB1) Protein Profile

Protein Summary

Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors.

Gene names and symbols associated with LIM Domain Binding 1 Proteins (LDB1)

  • LIM domain binding 1 (ldb1)
  • LIM domain binding 1 (Ldb1)
  • LIM domain binding 1 (LDB1)
  • LIM domain binding protein 1 (xldb1)
  • LIM-domain binding factor 1b (ldb1b)
  • chi protein
  • CLIM2 protein
  • ldb1 protein
  • NLI protein
  • xldb1 protein

Protein level used designations for LIM Domain Binding 1 Proteins (LDB1)

CLIM-2 , LDB-1 , LIM domain-binding factor CLIM2 , LIM domain-binding protein 1 , carboxyl-terminal LIM domain-binding protein 2 , mLdb1 , nuclear LIM interactor , cLdb1 , neural Src-interacting protein , neural src interacting protein , LIM domain-binding factor-1 , carboxy terminal LIM domain protein 2 , hLdb1 , LIM-domain binding factor 1

GENE ID SPECIES
380241 Xenopus laevis
16825 Mus musculus
395952 Gallus gallus
8861 Homo sapiens
477804 Canis lupus familiaris
309447 Rattus norvegicus
779363 Xenopus laevis
30576 Danio rerio
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