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LIM Domain and Actin Binding 1 Proteins (LIMA1)

LIMA1 encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. Additionally we are shipping LIMA1 Antibodies (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat LIMA1 LIMA1 300228  
LIMA1 51474 Q9UHB6
LIMA1 65970 Q9ERG0
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Top LIMA1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LIMA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for LIM Domain and Actin Binding 1 (LIMA1) Interaction Partners

Human LIM Domain and Actin Binding 1 (LIMA1) interaction partners

  1. EPLIN is functionally linked to molecules like actin and paxillin (show PXN Proteins) and has been implicated in a number of potential pathways to enhance metastatic potential

  2. a major activity of DNp73 is to establish initiation of the invasion-metastasis cascade via EPLIN-dependent IGF1R (show IGF1R Proteins) regulation

  3. EGF (show EGF Proteins) promotes epithelial-mesenchymal transition and induces degradation of EPLIN, a putative suppressor of prostate cancer metastasis.

  4. Together with the findings that EPLIN-alpha inhibits cellular growth and invasion, we conclude that EPLIN-alpha is a tumour suppressor of oesophageal cancer

  5. EPLIN clutch is necessary for stabilization of capillary structures in an angiogenesis model.

  6. EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.

  7. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

  8. expression of EPLIN-alpha in breast cancer is down-regulated in breast cancer cells .

  9. EPLIN protein may function during cytokinesis to maintain local accumulation of key cytokinesis proteins at the furrow.

Mouse (Murine) LIM Domain and Actin Binding 1 (LIMA1) interaction partners

  1. findings suggest that PINCH-1 (show LIMS1 Proteins) regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (show ILK Proteins) as well as EPLIN.

  2. Eplin-alpha transcription is regulated by actin-MAL-SRF signalling.

  3. EPLIN may function in growth control by associating with and regulating the actin cytoskeleton

  4. ERK-mediated phosphorylation of EPLIN contributes to actin filament reorganization and enhanced cell motility.

  5. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

LIMA1 Protein Profile

Protein Summary

This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.

Gene names and symbols associated with LIMA1

  • LIM domain and actin binding 1 (Lima1)
  • LIM domain and actin binding 1 (LIMA1)
  • LIM domain and actin binding 1 (lima1)
  • 1110021C24Rik protein
  • 3526402A12Rik protein
  • D15Ertd366e protein
  • Eplin protein
  • LIMA1 protein
  • MGC146397 protein
  • SREBP3 protein

Protein level used designations for LIMA1

LIM domain and actin-binding protein 1 , epithelial protein lost in neoplasm , LIM domain and actin binding 1 , epithelial protein lost in neoplasm beta , 1110021C24Rik , sterol regulatory element binding protein 3 , epithelial protein lost in neoplasm-a , epithelial protein lost in neoplasm-b , mEPLIN

GENE ID SPECIES
300228 Rattus norvegicus
451892 Pan troglodytes
779798 Xenopus (Silurana) tropicalis
51474 Homo sapiens
65970 Mus musculus
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