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LIM Homeobox 6 Proteins (LHX6)

LHX6 encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. Additionally we are shipping LIM Homeobox 6 Antibodies (74) and LIM Homeobox 6 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LHX6 26468 Q9UPM6
Rat LHX6 LHX6 311901  
LHX6 16874 Q9R1R0
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Top LIM Homeobox 6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LHX6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for LIM Homeobox 6 (LHX6) Interaction Partners

Human LIM Homeobox 6 (LHX6) interaction partners

  1. LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.

  2. LHX6 is a putative tumour suppressor gene with epigenetic silencing in lung cancer.

  3. LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2 (show PITX2 Proteins)) to regulate odontogenesis

  4. found positive association of LHX6 with Tourette syndrome in some European populations, not others. LHX6 demonstrates a high degree of population differentiation and is correlated with the North to South axis of European genetic variation.

  5. Hypermethylation of LHX6 is associated with cervical cancer.

  6. differentially methylated hypermethylation of LHX6 is a good cancer marker in HNSCC as well as in other kinds of neoplasias and confirm the importance of searching for markers of epigenetic dysregulation in cancer

Mouse (Murine) LIM Homeobox 6 (LHX6) interaction partners

  1. LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.

  2. Lhx6 and Lhx8 (show LHX8 Proteins) promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2 (show CDKN1C Proteins)

  3. Studies indicate that LIM (show PDLIM5 Proteins) homeobox (show PRRX1 Proteins) proteins Lhx6 and -8 mRNAs are primarily expressed in the ventral telencephalon, specifically in the medial ganglionic eminence (MGE) of the basal forebrain and in subsets of neurons in the striatum.

  4. The data of this study showed the molecular identity of Lhx6 mutants and introduce technologies to test mechanisms in GABAergic interneuron differentiation.

  5. Lhx6 plays an important role in the maturation of cortical interneurons and the formation of inhibitory circuits in the mammalian cortex

  6. Msx1 (show MSX1 Proteins) interacts with Lhx6 and Sna (show SNAI1 Proteins) in vivo. A network of transcription factors operates during early tooth morphogenesis.

  7. LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2 (show PITX2 Proteins)) to regulate odontogenesis

  8. Lhx6 and Lhx8 (show LHX8 Proteins) coordinately induce neuronal expression of Shh (show SHH Proteins) that controls the generation of interneuron progenitors.

  9. Lhx6 functions may be partially redundant in the mesenchyme of the secondary palate, but not in the palatal epithelium.

  10. Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus.

LIM Homeobox 6 (LHX6) Protein Profile

Protein Summary

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Gene names and symbols associated with LIM Homeobox 6 Proteins (LHX6)

  • LIM homeobox 1b (lhx1b)
  • LIM homeobox 6 (lhx6)
  • LIM homeobox 6 (LHX6)
  • LIM homeobox 6 (Lhx6)
  • LIM homeobox protein 6 (Lhx6)
  • LHX6 protein
  • Lhx6.1 protein
  • lhx7-A protein
  • lim6 protein
  • x-Lhx7 protein

Protein level used designations for LIM Homeobox 6 Proteins (LHX6)

LIM homeobox protein 6 , LIM homeobox 6 , LIM homeodomain transcription factor, N terminal-like , putative LIM homeodomain transcription factor, N terminal , LIM homeodomain protein , LIM/homeobox protein Lhx6-like , LIM homeodomain protein 6.1 , LIM/homeobox protein Lhx6 , LIM/homeobox protein Lhx6.1 , LIM-homeodomain protein 6.1

GENE ID SPECIES
30454 Danio rerio
378636 Xenopus laevis
698587 Macaca mulatta
735560 Pan troglodytes
772259 Gallus gallus
100014160 Monodelphis domestica
100435907 Pongo abelii
100484422 Ailuropoda melanoleuca
100583152 Nomascus leucogenys
26468 Homo sapiens
491354 Canis lupus familiaris
541261 Bos taurus
311901 Rattus norvegicus
445565 Danio rerio
16874 Mus musculus
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