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The protein encoded by LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. Additionally we are shipping LSS Antibodies (34) and LSS Kits (20) and many more products for this protein.
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liver-specific ablation of squalene synthase (show FDFT1 Proteins) inhibits hepatic cholesterol biosynthesis and induces hypolipidemia (show ANGPTL3 Proteins) without increasing significant mortality.
Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha (show NR1H3 Proteins)-mediated improvement of hepatic lipid profile.
Lanosterol synthase gene polymorphisms influence both the salt sensitivity of BP and changes in circulating EO in response to a low salt diet.
There were no significant differences in OSC mRNA expression at various stages of breast cancer, or between tumor and normal mammary cells.
two crystal structures of the human membrane protein OSC: the target protein with an inhibitor that showed cholesterol lowering in vivo opens the way for the structure-based design of new OSC inhibitors
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
, lanosterol synthase
, 2,3-epoxysqualene--lanosterol cyclase
, oxidosqualene--lanosterol cyclase
, 2,3-epoxysqualene-lanosterol cyclase
, oxidosqualene lanosterol cyclase
, 2,3-oxidosqualene: lanosterol cyclase