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anti-Latexin (LXN) Antibodies

LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. Additionally we are shipping Latexin Proteins (26) and Latexin Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LXN 56925 Q9BS40
LXN 17035 P70202
LXN 59073 Q64361
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Top anti-Latexin Antibodies at antibodies-online.com

Showing 10 out of 155 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Mouse Un-conjugated WB LXN  western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the LXN antibody detected the LXN protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of Latexin (arrow) using rabbit polyclonal Latexin Antibody (Center) (ABIN388260). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the LXN gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with Latexin antibody (Center) (ABIN388260), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated WB LXN antibody   western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the LXN  antibody detected the LXN  protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN190839 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC202769 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-LXN antibody (ABIN2455184), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LXN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LXN. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LXN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LXN. Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-LXN mouse monoclonal antibody. (ABIN2455096) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: LXNAntibody Dilution: 1.0ug/mlSample Tissue: A549 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details

LXN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Latexin Antibodies

  1. Human Polyclonal Latexin Primary Antibody for IHC, ELISA - ABIN190839 : de Haan: Latexin is a newly discovered regulator of hematopoietic stem cells. in Nature genetics 2007 (PubMed)
    Show all 3 references for ABIN190839

  2. Mouse (Murine) Monoclonal Latexin Primary Antibody for WB - ABIN659083 : Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007 (PubMed)
    Show all 2 references for ABIN659083

  3. Dog (Canine) Polyclonal Latexin Primary Antibody for EIA, IF - ABIN374848 : Kadouchi, Sakamoto, Tangjiao, Murakami, Kobayashi, Hoshino, Yamaguchi: Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN374848

  4. Mouse (Murine) Monoclonal Latexin Primary Antibody for WB - ABIN659082 : Pallarès, Bonet, García-Castellanos, Ventura, Avilés, Vendrell, Gomis-Rüth: Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN659082

More Antibodies against Latexin Interaction Partners

Human Latexin (LXN) interaction partners

  1. Results show that Lxn expression was clearly decreased in the pancreatic ductal adenocarcinoma tissues suggesting it that as a tumor suppressor that targets CD133-positive cancer cells.

  2. Lxn protein and mRNA expression levels in CD133+ miapaca-2 cells were significantly lower than those in CD133- cells.

  3. latexin is markedly downregulated in hepatocellular carcinoma specimens, compared to adjacent non-cancerous tissues.

  4. CD146 (show MCAM Antibodies) and Lxn increased tumor migration and invasion of thyroid cancer.

  5. The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.

  6. These results are consistent with a tumor suppressor role for latexin.

  7. Latexin expression is lost or greatly reduced in approximately 50% of human leukemia/lymphoma cell lines.

Mouse (Murine) Latexin (LXN) interaction partners

  1. Rps3 (show RPS3 Antibodies) knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 (show RPS3 Antibodies) pathway.

  2. These results are consistent with a tumor suppressor role for latexin.

  3. Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche.

  4. Data indicate that AAV-mediated latexin transduction or administration of a small molecule carboxypeptidase A inhibitor significantly reduced acetone-evoked nociceptive behavior after SNI.

  5. The crystal structure of mouse latexin, solved at 1.83 A resolution, shows no structural relationship with other carboxypeptidase inhibitors.

  6. Latexin is involved in the transmission of pain, since mice lacking this protein experience reducted pain sensitivity.

  7. promoter polymorphisms between the B6 and D2 alleles may affect Lxn gene expression and consequently influence the population size of hematopoietic stem cells.

  8. These results indicate that latexin is involved in BMP-2 (show BMP2 Antibodies)-induced chondrocyte differentiation and plays an important role in skeletogenesis and skeletal regeneration.

Latexin (LXN) Antigen Profile

Protein Summary

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.

Gene names and symbols associated with anti-Latexin (LXN) Antibodies

  • latexin (lxn) antibody
  • latexin (LXN) antibody
  • Latexin (lxn) antibody
  • latexin (LOC100346216) antibody
  • latexin (Lxn) antibody
  • ECI antibody
  • lxn antibody
  • TCI antibody
  • wu:fk66c02 antibody
  • zgc:103612 antibody

Protein level used designations for anti-Latexin (LXN) Antibodies

latexin , Latexin , MUM , endogenous carboxypeptidase inhibitor , tissue carboxypeptidase inhibitor , ECI , TCI

GENE ID SPECIES
494053 Danio rerio
703996 Macaca mulatta
771519 Gallus gallus
100195080 Salmo salar
100322883 Felis catus
100346216 Oryctolagus cuniculus
56925 Homo sapiens
17035 Mus musculus
59073 Rattus norvegicus
610062 Canis lupus familiaris
781644 Bos taurus
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