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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping LGALS7 Antibodies (73) and LGALS7 Kits (39) and many more products for this protein.
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Human LGALS7 Protein expressed in Escherichia coli (E. coli) - ABIN1047044
Madsen, Rasmussen, Flint, Gromov, Kruse, Honoré, Vorum, Celis: Cloning, expression, and chromosome mapping of human galectin-7. in The Journal of biological chemistry 1995
Show all 2 references for ABIN1047044
results indicate that an excess of galectin-7 leads to a destabilisation of adherens junctions associated with defects in epidermal repair
Overexpression of galectin-7 increased the resistance of melanoma cells to apoptosis while inducing de novo egr-1 (show EGR1 Proteins) expression.
In cardiac transplantation galectin-7 relates to acute allograft rejection and T-cell responses possibly as an accelerant.
Extracellular superoxide dismutase (show SOD3 Proteins) plays a role not only as a reactive oxygen species scavenger, but also as a pro-apoptotic factor via COX-2/galectin-7 pathways in the epidermis.
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
Data show that high levels of galectin-7 expression in breast cancer cells drastically increased their ability to metastasize to lungs and bones, and were restricted to high-grade breast carcinomas.
Galectin-3 (show LGALS3 Proteins) and galectin-7 play a role in corneal epithelial wound healing.
Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype.
Galectin-7 promotes maliganacy by upregulating MMP-9 (show MMP9 Proteins) gene expression.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19.
, lectin, galactose binding, soluble 7
, galectin 7B
, keratinocyte lectin 14
, lectin galactoside-binding soluble 7
, p53-induced gene 1 protein
, p53-induced protein 1