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Lectin, Galactoside-Binding, Soluble, 4 Proteins (LGALS4)

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Additionally we are shipping Lectin, Galactoside-Binding, Soluble, 4 Antibodies (80) and Lectin, Galactoside-Binding, Soluble, 4 Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LGALS4 16855 Q8K419
LGALS4 25474 P38552
LGALS4 3960 P56470
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Top Lectin, Galactoside-Binding, Soluble, 4 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$616.00
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,867.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,871.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,896.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details

LGALS4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced Lectin, Galactoside-Binding, Soluble, 4 Proteins

  1. Mouse (Murine) LGALS4 Protein expressed in Escherichia coli (E. coli) - ABIN1098441 : Huflejt, Jordan, Gitt, Barondes, Leffler: Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for ABIN1098441

More Proteins for Lectin, Galactoside-Binding, Soluble, 4 (LGALS4) Interaction Partners

Xenopus laevis Lectin, Galactoside-Binding, Soluble, 4 (LGALS4) interaction partners

  1. Xgalectin-VIa possesses different features from other cement gland genes and is a novel and useful marker of the cement gland in developing embryos.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 4 (LGALS4) interaction partners

  1. patterns of galectin-4 and galectin-6 expression in the normal and the dextran sodium sulfate (DSS (show PMP22 Proteins))-damaged digestive

  2. structure of galectin-4 and binding properties of the N-terminal domain carbohydrate-recognition domain (CRD)1 were further investigated and the crystal structure of CRD1 in complex with lactose was determined at 2.1 A resolution

  3. The galectin-4-mediated stimulation of CD4 (show CD4 Proteins)(+) T cells is shown to exacerbate chronic colitis and delay the recovery from acute intestinal injury

  4. While the CRD2 domain of galectin-4 has a high specificity and affinity for A type-2 alpha-GalNAc structures, the CRD1 domain has a broader specificity in correlation to the total binding profile.

  5. X-ray analysis of the N-terminal domain of colon cancer marker Gal-4 is revealed in complex with lactose (the basic building block of known galectin-4 carbohydrate ligands).

  6. galectin-4 plays a unique role in the intestine and assign a novel role of this protein in controlling intestinal inflammation by a selective induction of T cell apoptosis and cell cycle restriction

Human Lectin, Galactoside-Binding, Soluble, 4 (LGALS4) interaction partners

  1. The data suggests that arm-Gal4 has detrimental effects on Drosophila development and lifespan that are directly dependent upon parental inheritance

  2. The co-expression of galectin-4 and CNT3 (show SLC28A3 Proteins) proteins is not impaired in inflamed colon from patients with Crohn's disease, thereby anticipating the integrity of this system for drug targeting.

  3. Structural characterization of human galectin 4 C-terminal domain in terms its ligands binding specificity has been reported.

  4. some galectins, particularly galectin-3 and -4, showed the ability to drive clathrin-independent mechanisms of endocytosis.

  5. The results show galectin-4 expression closely associates with hepatocellular carcinoma (HCC (show FAM126A Proteins)) progression and might have potential use as a prognostic biomarker for HCC (show FAM126A Proteins) patients.

  6. Results suggest that galectin-3 (show LGALS3 Proteins), -4, -7 and -9 could be involved in the biology of inverted papillomas.

  7. Galectin-4 plays an important role in metastatic process of lung adenocarcinoma.

  8. The increased circulation of galectins -2, -4 and -8 in cancer patients contributes substantially to the increased circulation of G-CSF (show CSF3 Proteins), IL-6 (show IL6 Proteins) and MCP-1 (show CCL2 Proteins) by interaction with the blood vascular endothelium

  9. Data indicate that galectin-4 elicits tumor promotion in vitro and in vivo through activation of IL-6 (show IL6 Proteins)/NF-kappaB (show NFKB1 Proteins)/STAT3 (show STAT3 Proteins) signaling.

  10. Data indicate that simultaneous determination of serum galectin-3 (show LGALS3 Proteins) and -4 levels in a single assay provides a high specificity and sensitivity in distinguishing colorectal cancer patients without metastases from those with liver metastases.

Lectin, Galactoside-Binding, Soluble, 4 (LGALS4) Protein Profile

Protein Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer.

Gene names and symbols associated with LGALS4

  • lectin, galactoside-binding, soluble, 4 (LGALS4)
  • lectin, galactoside-binding, soluble, 4 (lgals4)
  • Galectin-4 (leg4)
  • lectin, galactose binding, soluble 4 (Lgals4)
  • lectin, galactoside-binding, soluble, 4 (Lgals4)
  • gal-4 protein
  • GAL4 protein
  • galectin-4 protein
  • L-36 protein
  • L36LBI protein
  • L36LBP protein
  • LGALS4 protein
  • MGC86186 protein
  • xgalectin-VIa protein

Protein level used designations for LGALS4

lectin, galactoside-binding, soluble, 4 , lectin, galactoside-binding, soluble, 4 (galectin 4) , galectin family xgalectin-VIa , Galectin-4 , galectin-4 , lactose-binding lectin 4 , gal-4 , L-36 lactose binding protein , L-36 lactose-binding protein , L36LBP , Lectin galactose binding soluble 4 (Galectin-4) , Lectin, galactose binding, soluble 4 (Galectin-4) , antigen NY-CO-27 , galectin 4

GENE ID SPECIES
456011 Pan troglodytes
694195 Macaca mulatta
398443 Xenopus laevis
100286643 Salmo salar
16855 Mus musculus
614804 Bos taurus
397041 Sus scrofa
100009464 Oryctolagus cuniculus
25474 Rattus norvegicus
3960 Homo sapiens
484521 Canis lupus familiaris
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