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Leucine Rich Repeat Containing 4 Proteins (LRRC4)

LRRC4 is significantly downregulated in primary brain tumors. Additionally we are shipping Leucine Rich Repeat Containing 4 Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LRRC4 64101 Q9HBW1
LRRC4 192198 Q99PH1
LRRC4 641521 Q45R42
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Top Leucine Rich Repeat Containing 4 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$651.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,498.00
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$584.38
Details

LRRC4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced Leucine Rich Repeat Containing 4 Proteins

  1. Human LRRC4 Protein expressed in HEK-293 Cells - ABIN2181482 : Zhang, Wang, Fan, Wang, Cao, Tang, Peng, Li, Li, Gan, Liu, Li, Shen, Li: Expression and functional characterization of LRRC4, a novel brain-specific member of the LRR superfamily. in FEBS letters 2005 (PubMed)

More Proteins for Leucine Rich Repeat Containing 4 (LRRC4) Interaction Partners

Human Leucine Rich Repeat Containing 4 (LRRC4) interaction partners

  1. polymorphisms and haplotypes in the LRRC4 may have a role in pituitary adenoma in a Chinese population

  2. Disturbing miR (show MLXIP Proteins)-182 and -381 inhibits BRD7 (show BRD7 Proteins) transcription and glioma growth by directly targeting LRRC4.

  3. LRRC4 inhibited the miR (show MLXIP Proteins)-185 pathway function in glioma

  4. Potentially, modulation of LRRC4 or STMN1 (show STMN1 Proteins) expression may be useful for design of new therapies for the intervention of glioma

  5. As a glioma suppressor, LRRC4 inhibits the endogenous expression of small regulatory microRNA hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-381 and decreases cell proliferation and tumor growth in cultured glioma cells.

  6. LRRC4 may play an important role in maintaining normal function and suppressing tumorigenesis in the central nervous system.

  7. LRRC4 gene might be involved in tumor suppression by restraining DNA synthesis and nucleoli organizer regions-associated proteins.

  8. these studies represent the first cDNA array analysis of the effects of LRRC4 on the involvement of different neurobiological genes in U251MG glioblastoma cells and provide new insights into the function of LRRC4 in glioma

  9. LRRC4 plays a major role in suppressing U251 cell proliferation by regulating the extracellular signal-regulated kinase (ERK (show EPHB2 Proteins))/Akt (show AKT1 Proteins)/NF-kappaBp65, STAT3 (show STAT3 Proteins), and JNK2 (show MAPK9 Proteins)/c-Jun (show JUN Proteins) pathways.

  10. LRRC4 may be a negative regulator of the RPTP-zeta (show PTPRZ1 Proteins) receptor, and contribute to suppressing the invasion ability of gliomas cells

Mouse (Murine) Leucine Rich Repeat Containing 4 (LRRC4) interaction partners

  1. our results identify NGL-2 as a central component of pathway-specific development in the outer retina.

  2. These results demonstrate that NGL-2 is critical for pathway-specific synapse development and functional integration of distinct inputs.

  3. LRRC4 may play an important role in maintaining normal function and suppressing tumorigenesis in the central nervous system.

  4. Together, these findings provide clues to the function of LRRC4 as a negative regulator of cell growth and underscore a link between the above-mentioned cyclins, cyclin (show PCNA Proteins)-associated molecules and tumorigenicity.

Leucine Rich Repeat Containing 4 (LRRC4) Protein Profile

Protein Summary

This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown.

Gene names and symbols associated with LRRC4

  • leucine rich repeat containing 4 (LRRC4)
  • leucine rich repeat containing 4 (Lrrc4)
  • MBAG1 protein
  • Nag14 protein
  • NGL-2 protein
  • NLG-2 protein

Protein level used designations for LRRC4

brain tumor associated protein LRRC4 , brain tumor-associated protein BAG , leucine-rich repeat-containing 4 , leucine-rich repeat-containing protein 4 , nasopharyngeal carcinoma-associated gene 14 protein , netrin-G2 ligand , leucine rich repeat containing 4 protein , netrin-G1 ligand , LIBG-like protein , LRRC4-like protein , brain tumor-associated protein MBAG1 , NGL-2 , protein NGL-2

GENE ID SPECIES
100056742 Equus caballus
64101 Homo sapiens
607997 Canis lupus familiaris
525767 Bos taurus
192198 Mus musculus
641521 Rattus norvegicus
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