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LOXL4 encodes a member of the lysyl oxidase gene family. Additionally we are shipping Lysyl Oxidase-Like 4 Antibodies (60) and Lysyl Oxidase-Like 4 Proteins (7) and many more products for this protein.
Showing 9 out of 19 products:
Human LOXL4 ELISA Kit for Sandwich ELISA - ABIN421172
Jiang, Sima, Wang, Zhang, Sun, Chen, Li: Identification of the involvement of LOXL4 in generation of keratocystic odontogenic tumors by RNA-Seq analysis. in International journal of oral science 2014
These results demonstrate that weak LOXL4 expression leads to remodeling of the extracellular matrix through induction of collagen synthesis, deposition, and structural changes.
Although expression of LOXL4 is not statistically associated with neck metastases, we showed that LOXL4 expression significantly increased in laryngeal cancer.
In hepatocellular carcinoma, low LOXL4 expression was associated with lower overall survival rates and higher cumulative recurrence rates.
These results provide a set of the essential genes in this newly identified miR (show MLXIP ELISA Kits)-193a-3p/LOXL4/Oxidative Stress axis.
High Lysyl oxidase-like 4 promotes proliferation and metastasis of gastric cancer via FAK (show PTK2 ELISA Kits)/Src (show SRC ELISA Kits) pathway.
data suggest that abnormal expression of LOXL4 of KCOT may enhance angiogenesis in KCOT, which may help to promote the locally aggressive biological behavior of KCOT.
TGF-beta1 (show TGFB1 ELISA Kits) induced injured MCL (show FH ELISA Kits) to express more LOXs than injured ACL (show ACLY ELISA Kits) (up to 1.85-fold in LOX (show LOX ELISA Kits), 2.21-fold in LOXL-1 (show LOXL1 ELISA Kits), 1.71-fold in LOXL-2 (show LOXL2 ELISA Kits), 2.52-fold in LOXL-3 (show LOXL3 ELISA Kits) and 3.32-fold in LOXL-4).
Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer.
The human lysyl oxidase-like 4 gene does not confer increased genotypic risk for adolescent idiopathic scoliosis.
SNPs in the lysyl oxidase-like protein 4 and complement component 3 (show C3 ELISA Kits) genes are associated with increased risk for endometriosis and endometriosis-associated infertility in a Puerto Rican population.
Overexpression of the lysyl oxidase-like 4 gene is associated with metastatic head/neck carcinoma.
These results suggest that TGF-beta1 (show TGFB1 ELISA Kits)-dependent expression of LOXL4 plays a role in vascular extracellular matrix homeostasis, contributing to vascular processes associated with extracellular matrix remodeling and fibrosis.
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
lysyl oxidase-like 4
, lysyl oxidase related protein homolog-like
, lysyl oxidase homolog 4-like
, lysyl oxidase homolog 4
, lysyl oxidase-like protein 4
, lysyl oxidase-related protein C
, lysyl oxidase related C
, lysyl oxidase-like 4 pseudogene