You are viewing an incomplete version of our website. Please click to reload the website as full version.

MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) Proteins (MAD2L1)

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Additionally we are shipping MAD2L1 Antibodies (117) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAD2L1 56150 Q9Z1B5
MAD2L1 4085 Q13257
Rat MAD2L1 MAD2L1 297176  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MAD2L1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MAD2L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced MAD2L1 Proteins

  1. Human MAD2L1 Protein expressed in Escherichia coli (E. coli) - ABIN2181494 : Luo, Fang, Coldiron, Lin, Yu, Kirschner, Wagner: Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. in Nature structural biology 2000 (PubMed)
    Show all 2 references for ABIN2181494

  2. Human MAD2L1 Protein expressed in Escherichia coli (E. coli) - ABIN667562 : Habu, Kim, Weinstein, Matsumoto: Identification of a MAD2-binding protein, CMT2, and its role in mitosis. in The EMBO journal 2002 (PubMed)
    Show all 2 references for ABIN667562

More Proteins for MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) Interaction Partners

Mouse (Murine) MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (show MXI1 Proteins)

  2. study shows that Mad2 (show MXI1 Proteins) is a novel substrate for CCP6 (show AGBL4 Proteins) in megakaryocytes; Mad2 (show MXI1 Proteins) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis

  3. Exacerbating chromosome missegregation in CENP-E (show CENPE Proteins)+/- mice by reducing levels of another mitotic checkpoint component (show BUB3 Proteins), Mad2 (show MXI1 Proteins), results in elevated cell death and decreased tumor formation compared with reduction of either protein alone.

  4. Mad2 (show MXI1 Proteins) is also repressed by p53 (show TP53 Proteins) and its upregulation is required for chromosome instability in a p53 (show TP53 Proteins) mutant tumor model

  5. Data show that Mad2 (show MXI1 Proteins) haploinsufficiency is protective in the presence of a cycle-specific DNA synthesis agent in vivo, and Ape1/Ref-1 (show APEX1 Proteins) inhibitor in vitro.

  6. Pcid2 (show PCID2 Proteins) is essential for B cell survival through the regulation of MAD2 (show MXI1 Proteins) expression during B cell differentiation

  7. tumours that experience transient Mad2 (show MXI1 Proteins) overexpression and consequent chromosome instability recur at markedly elevated rates

  8. a functional Mad2 (show MXI1 Proteins)-dependent spindle checkpoint exists during the first meiotic division in mammalian oocytes

  9. Data show that the loss of Trrap leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap-mediated transcription of the mitotic checkpoint (show BUB3 Proteins) proteins Mad1 (show MXD1 Proteins) and Mad2 (show MXI1 Proteins).

  10. that Brca1 (show BRCA1 Proteins)(Delta11/Delta11) cells displayed decreased expression of a number of genes that are involved in the spindle checkpoint, including Mad2 (show MXI1 Proteins)

Human MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. Studied the folding/unfolding process of the open and closed conformers of human Mad2.

  2. MAD1L1 (show MAD1L1 Proteins) Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer

  3. p31comet-induced cell death is mediated by interactions with Mad2

  4. MAD2L1 and BUB1 (show BUB1 Proteins) may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

  5. We also show that replication perturbations result in relocalization of MAD1 (show MXD1 Proteins)/MAD2 in human cells, suggesting that the role of SAC (show ADCY10 Proteins) in DNA repair is conserved.

  6. Data indicate the structure of the intermediate conformer of the multistate checkpoint protein mitotic arrest deficient 2 (Mad2) protein.

  7. WT1 (show WT1 Proteins) has a role in interacting MAD2 and regulating mitotic checkpoint (show BUB3 Proteins) function

  8. In conclusion, the results presented here suggest that Mad2 and BubR1 (show BUB1B Proteins) could be used as prognostic markers of tumor progression and new pharmacological targets in the treatment for gastric cancer .

  9. Co-depletion of MAD2 and BUBR1 (show BUB1B Proteins) causes cell cycle arrest and cell death in addition to aneuploidy.

  10. hMAD2 also binds to the hREV7 (show MAD2L2 Proteins)-binding sequence in hREV3, whereas hMAD2 does not bind to a similar sequence in ADAM9 (show ADAM9 Proteins) or ELK-1 (show ELK1 Proteins) and hREV7 (show MAD2L2 Proteins) does not bind to the hMAD2-binding sequence in hMAD1 or hCDC20.

MAD2L1 Protein Profile

Protein Summary

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Gene names and symbols associated with MAD2L1

  • MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1)
  • MAD2 mitotic arrest deficient-like 1 (yeast) (mad2l1)
  • MAD2 mitotic arrest deficient-like 1 (mad2l1)
  • MAD2 mitotic arrest deficient-like 1 (MAD2L1)
  • MAD2 mitotic arrest deficient-like 1 (yeast) (LOC100218172)
  • MAD2 mitotic arrest deficient-like 1 (Mad2l1)
  • MAD2 mitotic arrest deficient-like 1 (yeast) (Mad2l1)
  • AA673185 protein
  • cb408 protein
  • HSMAD2 protein
  • MAD2 protein
  • MAD2L1 protein
  • XMad2 protein
  • zgc:112133 protein

Protein level used designations for MAD2L1

MAD2-like 1 , mitotic spindle assembly checkpoint protein MAD2A , spindle assembly checkpoint protein Mad2 , MAD2 mitotic arrest deficient-like 1 (yeast) , MAD2 mitotic arrest deficient-like 1 , MAD2 (mitotic arrest deficient, homolog)-like 1 , MAD2-like protein 1 , mitotic arrest deficient 2-like protein 1 , MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 , mitotic arrest deficient, yeast, homolog-like 1

GENE ID SPECIES
461661 Pan troglodytes
550434 Danio rerio
708574 Macaca mulatta
787996 Bos taurus
100125170 Xenopus (Silurana) tropicalis
100137358 Papio anubis
100218172 Taeniopygia guttata
56150 Mus musculus
380433 Xenopus laevis
4085 Homo sapiens
422675 Gallus gallus
476070 Canis lupus familiaris
337870 Bos taurus
297176 Rattus norvegicus
Selected quality suppliers for MAD2L1 Proteins (MAD2L1)
Did you look for something else?