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MAD2L1 Binding Protein Proteins (MAD2L1BP)

The protein encoded by MAD2L1BP was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). Additionally we are shipping MAD2L1BP Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat MAD2L1BP MAD2L1BP 316237  
MAD2L1BP 9587 Q15013
MAD2L1BP 66591 Q9DCX1
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Top MAD2L1BP Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MAD2L1BP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced MAD2L1BP Proteins

  1. Human MAD2L1BP Protein expressed in Escherichia coli (E. coli) - ABIN667695 : Habu, Kim, Weinstein, Matsumoto: Identification of a MAD2-binding protein, CMT2, and its role in mitosis. in The EMBO journal 2002 (PubMed)
    Show all 2 references for ABIN667695

More Proteins for MAD2L1 Binding Protein (MAD2L1BP) Interaction Partners

Human MAD2L1 Binding Protein (MAD2L1BP) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (show MAD2L1 Proteins)

  2. the oligomeric form of TRIP13 (show TRIP13 Proteins) binds both p31 (show ATP6V1E1 Proteins)(comet) and MCC (show MCC Proteins)

  3. joint action of TRIP13 (show TRIP13 Proteins) and p31 (show ATP6V1E1 Proteins)(comet) also promotes the release of Mad2 (show MAD2L1 Proteins) from MCC (show MCC Proteins), participates in the complete disassembly of MCC (show MCC Proteins) and abrogates checkpoint inhibition of APC (show APC Proteins)/C

  4. Altered p31 (show ATP6V1E1 Proteins)(Comet):Mad2 (show MAD2L1 Proteins) expression ratios may provide new insight into altered spindle assembly checkpoint function and the generation of chromosomal instability in tumors.

  5. attenuating the affinity of p31 (show ATP6V1E1 Proteins)(Comet) for Mad2 (show MAD2L1 Proteins) by phosphorylation promotes SAC (show ADCY10 Proteins) activity in mitosis. Specifically, phosphorylation of Ser (show SIGLEC1 Proteins)-102 weakens p31 (show ATP6V1E1 Proteins)(Comet)-Mad2 (show MAD2L1 Proteins) binding and enhances p31 (show ATP6V1E1 Proteins)(Comet)-mediated bypass of the SAC (show ADCY10 Proteins).

  6. study found p31 (show ATP6V1E1 Proteins)(comet) traffics on and off kinetochores and also present in the cytosol; Cells depleted of p31 (show ATP6V1E1 Proteins)(comet) arrest in metaphase with mature bipolar kinetochore-microtubule attachments; propose that p31 (show ATP6V1E1 Proteins)(comet) is an essential component of machinery that silences the checkpoint during each cell cycle

  7. the importance of p31 (show ATP6V1E1 Proteins)(comet) in checkpoint silencing and its potential as a target for antimitotic therapies.

  8. The binding of p31 (show ATP6V1E1 Proteins)(comet) to Mad2 (show MAD2L1 Proteins) in mitotic checkpoint (show BUB3 Proteins) complex may trigger a conformational change in Cdc20 (show CDC20 Proteins) that facilitates its phosphorylation by Cdk (show CDK4 Proteins), and that the latter process may promote its dissociation from BubR1 (show BUB1B Proteins).

  9. both p31 (show ATP6V1E1 Proteins)(comet) and ubiquitination of Cdc20 (show CDC20 Proteins) are critical mechanisms of checkpoint inactivation. They act redundantly to promote Mad2 (show MAD2L1 Proteins) dissociation from Cdc20 (show CDC20 Proteins)

  10. p31 (show ATP6V1E1 Proteins)(comet) negatively regulates the spindle assembly checkpoint by extracting Mad2 (show MAD2L1 Proteins) from the MCC (show MCC Proteins).

Mouse (Murine) MAD2L1 Binding Protein (MAD2L1BP) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (show MXI1 Proteins)

MAD2L1BP Protein Profile

Protein Summary

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with MAD2L1BP

  • MAD2L1 binding protein (Mad2l1bp)
  • MAD2L1 binding protein (MAD2L1BP)
  • 0610009D16Rik protein
  • 2510031P20Rik protein
  • AU018945 protein
  • AW550977 protein
  • C76045 protein
  • CMT2 protein
  • CMT2A protein
  • CMT2B protein
  • MAD2L1BP protein
  • Mad2lbp protein
  • mKIAA0110 protein
  • RP1-261G23.6 protein

Protein level used designations for MAD2L1BP

MAD2L1-binding protein , MAD2L1 binding protein , caught by MAD2 protein

GENE ID SPECIES
316237 Rattus norvegicus
421448 Gallus gallus
462721 Pan troglodytes
474916 Canis lupus familiaris
615542 Bos taurus
701099 Macaca mulatta
9587 Homo sapiens
66591 Mus musculus
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