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Maelstrom Spermatogenic Transposon Silencer Proteins (MAEL)

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Additionally we are shipping MAEL Kits (4) and MAEL Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAEL 98558 Q8BVN9
MAEL 84944 Q96JY0
Rat MAEL MAEL 364039  
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Top MAEL Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 25 μg Log in to see 9 Days
$591.43
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,169.83
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,213.83
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,213.83
Details

MAEL Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaction Partners

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. MAEL HMG (show SSRP1 Proteins)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (show TES Proteins)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (show PABPC1 Proteins) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (show FBN1 Proteins).

  2. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (show AKT1 Proteins)/GSK-3beta/Snail (show SNAI1 Proteins) signaling.

  3. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (show HELLS Proteins).

MAEL Protein Profile

Protein Summary

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Gene names and symbols associated with MAEL

  • maelstrom homolog (Drosophila) (Mael)
  • maelstrom homolog (Drosophila) (MAEL)
  • maelstrom spermatogenic transposon silencer (MAEL)
  • maelstrom spermatogenic transposon silencer (Mael)
  • protein maelstrom homolog (LOC100737640)
  • 4933405K18Rik protein
  • AU019877 protein
  • CT128 protein
  • RGD1309333 protein
  • RP11-102C16.1 protein
  • SPATA35 protein

Protein level used designations for MAEL

protein maelstrom homolog , cancer/testis antigen 128 , maelstrom homolog , spermatogenesis associated 35

GENE ID SPECIES
98558 Mus musculus
541073 Bos taurus
100048945 Sus scrofa
84944 Homo sapiens
364039 Rattus norvegicus
100737640 Sus scrofa
Selected quality suppliers for MAEL Proteins (MAEL)
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