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Major Histocompatibility Complex, Class II, DQ alpha 1 Proteins (HLADQA1)

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. Additionally we are shipping Major Histocompatibility Complex, Class II, DQ alpha 1 Antibodies (63) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLADQA1 3117 P01909
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Top Major Histocompatibility Complex, Class II, DQ alpha 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

HLADQA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) Interaction Partners

Human Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) interaction partners

  1. HLA-DQA1 (show HLA-DQA2 Proteins)*0102 and HLA-DQB1 (show HLA-DQB1 Proteins)*0201 alleles may be involved in the production of anti-beta2-glycoprotein I antibody in recurrent miscarriage patients.

  2. DQA1*0501 had significant negative association with MuSK (show MUSK Proteins) myasthenia gravis.

  3. The observed positive association between integrated HIV-1 DNA load and frequency of CD8 (show CD8A Proteins)(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.

  4. We found association of three variants in the region harboring genes encoding the class II human leukocyte antigens (HLAs): both located between HLA-DQA1 (show HLA-DQA2 Proteins) and HLA-DRB1 (show HLA-DRB1 Proteins)

  5. Pharmacoresistant temporal lobe epilepsy associated with mesial hippocampal sclerosis is not determined by HLA class II alleles in the DRB1 (show RBM45 Proteins), DQB1, and DQA1 regions but the HLA DRB1 (show HLA-DRB1 Proteins)*1302 allele exhibited a tendency to behave as a susceptibility factor

  6. Suggest that the DQA1*0103/CD74 (show CD74 Proteins) dimer may result in presentation of unique antigens and susceptibility to develop arthritis.

  7. HLA-DQA1 alleles contribute to the susceptibility of unexplained recurrent spontaneous abortion among ethnic Han Chinese.

  8. No significant association with tuberculosis risk was found in any HLA-DQA1 (show HLA-DQA2 Proteins) allele.

  9. The protective effects against type 1 diabetes mellitus of HLA-DQA1 (show HLA-DQA2 Proteins)*01:01, HLA-DQB1 (show HLA-DQB1 Proteins)*05:03, *06:02, *06:03, and *06:04 were robustly suggested by all indicators of meta-analyses. (Meta-analysis)

  10. In Asian population, the protective gene HLA-DQB1 (show HLA-DQB1 Proteins)*0303 and the susceptible genes HLA-DQB1 (show HLA-DQB1 Proteins)*0401, HLA-DQA1 (show HLA-DQA2 Proteins)*0103 and HLA-DQA1 (show HLA-DQA2 Proteins)*0301 in Helicobacter pylori infection were established by meta-analysis.

Major Histocompatibility Complex, Class II, DQ alpha 1 (HLADQA1) Protein Profile

Protein Summary

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons\; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Gene names and symbols associated with HLADQA1

  • major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1)
  • CD protein
  • CELIAC1 protein
  • DQ-A1 protein
  • GSE protein
  • HLA-DQA protein

Protein level used designations for HLADQA1

DC-1 alpha chain , DC-alpha , HLA class II histocompatibility antigen, DQ alpha 1 chain , HLA class II histocompatibility antigen, DQ(W3) alpha chain , HLA-DCA , MHC HLA-DQ alpha , MHC class II DQA1 , MHC class II HLA-D alpha glycoprotein , MHC class II HLA-DQ-alpha-1 , MHC class II antigen , MHC class II surface glycoprotein , leucocyte antigen DQA1 , leukocyte antigen alpha chain

GENE ID SPECIES
3117 Homo sapiens
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