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anti-Male Germ Cell-Associated Kinase (MAK) Antibodies

The product of MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Additionally we are shipping MAK Kits (7) and MAK Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAK 116904  
MAK 4117 P20794
MAK 25677 P20793
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Top anti-MAK Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MAK Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells treated with PMA 125ng/ml 30', using MAK (Phospho-Tyr159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of MAK (arrow) using MAK Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells, using MAK (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MAK (arrow) using MAK Antibody (C-term) (ABIN391782). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MAK gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB MAK Antibody (C-term) (ABIN1881520) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the MAK antibody detected the MAK protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to MAK on HepG2 cell (antibody concentration 10 µg/mL). MAK monoclonal antibody (M01), clone 3E5 Western Blot analysis of MAK expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

MAK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MAK Antibodies

  1. Human Monoclonal MAK Primary Antibody for IF, WB - ABIN393396 : Fu, Larson, Chitta, Parker, Turk, Lawrence, Kaldis, Galaktionov, Cohn, Shabanowitz, Hunt, Sturgill: Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. in Molecular and cellular biology 2006 (PubMed)
    Show all 5 references for ABIN393396

  2. Human Polyclonal MAK Primary Antibody for WB - ABIN1881520 : Ma, Xia, Desai, Boucher, Guan, Shih, Shi, deVere White, Chen, Tepper, Kung: Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. in Cancer research 2006 (PubMed)
    Show all 5 references for ABIN1881520

  3. Human Polyclonal MAK Primary Antibody for IHC (p), WB - ABIN391782 : Xia, Robinson, Ma, Chen, Wu, Qiu, Kung: Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 references for ABIN391782

  4. Human Polyclonal MAK Primary Antibody for ELISA, WB - ABIN1533086 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1533086

  5. Human Polyclonal MAK Primary Antibody for EIA, IHC (p) - ABIN359695 : Woodle, Newman, Cohen: Sterically stabilized liposomes: physical and biological properties. in Journal of drug targeting 1995 (PubMed)
    Show all 2 references for ABIN359695

  6. Human Polyclonal MAK Primary Antibody for ELISA, WB - ABIN1532053 : Greenman, Stephens, Smith, Dalgliesh, Hunter, Bignell, Davies, Teague, Butler, Stevens, Edkins, OMeara, Vastrik, Schmidt, Avis, Barthorpe, Bhamra, Buck, Choudhury, Clements, Cole, Dicks, Forbes, Gray et al.: Patterns of somatic mutation in human cancer genomes. ... in Nature 2007 (PubMed)
    Show all 2 references for ABIN1532053

More Antibodies against MAK Interaction Partners

Mouse (Murine) Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. the expressions of ICK/MAK/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  2. Cardiomyopathy developed in mice deficient for alpha-kinase 3 (ALPK3 (show ALPK3 Antibodies))

  3. Results suggest that Mak is essential for the regulation of ciliary length and is required for the long-term survival of photoreceptors.

  4. data show that function of MAK is not essential for spermatogenesis and male fertility.

Human Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. We identified the MAK and DHDDS (show DHDDS Antibodies) mutations homozygously in only 2.1% and 0.8%, respectively, of patients of mixed ethnicity, but in 25.7% and 8.6%, respectively, of cases reporting Jewish ancestry

  2. Nonsense and missense mutations in MAK give rise to a non-syndromic recessive RP phenotype without apparent extra-ocular features.

  3. the expressions of ICK/MAK/MOK (show MOK Antibodies) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  4. In glioblastoma cells with deregulated high levels of CCRK (show CDK20 Antibodies), its depletion restores cilia through ICK (show ICK Antibodies) and an ICK (show ICK Antibodies)-related kinase MAK, thereby inhibiting glioblastoma cell proliferation.

  5. these data implicate MAK in both adrogen receptor activation and chromosomal instability, acting in both early and late prostate cancer development.

  6. The patterns of disease expression in the MAK form of arRP showed some resemblance to patterns described in autosomal dominant RP, especially the form caused by RP1 (show STK19 Antibodies) mutations.

  7. Exome sequencing to identify a homozygous Alu insertion in exon 9 of male germ cell-associated kinase (MAK) as the cause of disease in an isolated individual with retinitis pigmentosa.

  8. Exome sequencing combined with this approach identified a homozygous nonsense mutation in male germ cell-associated kinase (MAK) in the single affected member of a consanguineous Turkish family with retinitis pigmentosa.

  9. MAK plays a general role in androgen receptor(AR (show AR Antibodies)) function in prostate cancer cells and is likely to be a general coactivator of AR in prostate tissues.

  10. MRK (show ICK Antibodies) phosphorylates Scythe (show BAT3 Antibodies) at T1080 in vitro as determined by site-directed mutagenesis and mass spectrometry, supporting the consensus and suggesting Scythe (show BAT3 Antibodies) as a physiological substrate for MRK (show ICK Antibodies).

MAK Antigen Profile

Protein Summary

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAK

  • male germ cell-associated kinase (MAK) antibody
  • male germ cell-associated kinase (mak) antibody
  • male germ cell-associated kinase (LOC100357745) antibody
  • alpha-kinase 3 (Alpk3) antibody
  • male germ cell-associated kinase (Mak) antibody
  • A930010O05Rik antibody
  • AW319487 antibody
  • D330016D04 antibody
  • dJ417M14.2 antibody
  • fj04c02 antibody
  • Ick antibody
  • MAK antibody
  • MGC82717 antibody
  • MGC146434 antibody
  • Midori antibody
  • mKIAA1330 antibody
  • RP62 antibody
  • wu:fj04c02 antibody
  • xmak antibody
  • zgc:56603 antibody

Protein level used designations for MAK

male germ cell-associated kinase , serine/threonine-protein kinase MAK-like , alpha-protein kinase 3 , myocyte induction differentiation originator , myocytic induction/differentiation originator , male germ cell-associated kinase retinal-enriched isoform , serine/threonine protein kinase MAK , serine/threonine-protein kinase MAK , protein kinase RCK , intestinal cell kinase

GENE ID SPECIES
420859 Gallus gallus
447015 Xenopus laevis
698353 Macaca mulatta
746604 Pan troglodytes
780268 Xenopus (Silurana) tropicalis
100019665 Monodelphis domestica
100051342 Equus caballus
100082794 Ornithorhynchus anatinus
100357745 Oryctolagus cuniculus
100469313 Ailuropoda melanoleuca
100603418 Nomascus leucogenys
116904 Mus musculus
4117 Homo sapiens
478721 Canis lupus familiaris
536048 Bos taurus
25677 Rattus norvegicus
17152 Mus musculus
335339 Danio rerio
Selected quality suppliers for anti-MAK (MAK) Antibodies
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