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Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase Proteins (MGAT3)

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Additionally we are shipping MGAT3 Antibodies (59) and MGAT3 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MGAT3 17309  
MGAT3 4248 Q09327
Rat MGAT3 MGAT3 29582 Q02527
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Top MGAT3 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

MGAT3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3) Interaction Partners

Mouse (Murine) Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3) interaction partners

  1. The MGAT3 and bisected complex N-glycans retard mouse mammary tumor progression; identification of key galectins that promote mammary tumor progression in mice is not straightforward because the galectin genes are expressed; and high levels of MGAT3.

  2. data suggest that Fut8 (show FUT8 Proteins)(-/-) mice adapted to oxidative stress, both ex vivo and in vivo, by inducing various genes including GnT-III, which may compensate for the loss of core fucose functions

  3. Mgat3 glycogene expression and GnT-III-mediated glycosylation, specifically on E-cadherin (show CDH1 Proteins), is a novel and major component of the Epithelial-Mesenchymal-Transition and the reverted process, Mesenchymal-Epithelial-Transition mechanism.

  4. Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor beta1 (TGF-beta1 (show TGFB1 Proteins)) in epithelial cell lines

  5. GnT-III expression may be precisely regulated by the interplay of E-cadherin (show CDH1 Proteins)-catenin complex-mediated cell-cell adhesion and Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling

  6. upregulation of GnT-III in AD brains may represent an adaptive response to protect them from additional beta-amyloid production

  7. mice homozygous for the Mgat3T37 mutation that express truncated GlcNAc-TIII from two mutant alleles suffer neurological and other consequences

  8. beta1,4-N-acetylglucosaminyltransferase III inhibits the function of alpha5beta1 integrin

  9. An E-cadherin (show CDH1 Proteins)-dependent pathway plays a critical role in regulation of GnT-III expression; changes in GnT-III expression presumably contribute to intracellular signaling transduction during tissue development and homeostasis.

Human Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3) interaction partners

  1. High expression of alpha2,6-sialylation on the cell surface could affect the anti-migratory role of GnT-III, which provides an insight into the mechanistic roles of GnT-III in tumor metastasis.

  2. Mgat3 plays an important role in early spontaneous miscarriage in humans.

  3. MGAT3 protein and gene expression in in uveal and cutaneous melanoma cells

  4. HS5 cells had significantly enhanced levels of bisecting N-glycans (catalyzed by MGAT3 whereas HS27a cells had enhanced levels of Galbeta1,4GlcNAc.

  5. GnT-III determines E-cadherin (show CDH1 Proteins)-mediated tumor suppression, and GnT-V (show MGAT5 Proteins) regulates E-cadherin (show CDH1 Proteins)-mediated tumor invasion.

  6. Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor beta1 (TGF-beta1 (show TGFB1 Proteins)) in epithelial cell lines

  7. MGAT3 mRNA biomarker may characterize subgroups of Alzheimer's disease patients with different disease progression.

  8. the modulation of glycosyltransferases MGAT3 and MGAT5 (show MGAT5 Proteins) by synthetic N-acetyl-D-glucosamine-calix[4]arene correlated with the improvement of NK cell effector functions and the augmentation of tumor cells sensitivity to NK cell-mediated cytotoxicity.

  9. upregulation of GnT-III in AD brains may represent an adaptive response to protect them from additional beta-amyloid production

  10. down-regulation of hydrogen peroxide-induced PKC delta (show PKCd Proteins) activation in cells transfected with this enzyme

MGAT3 Protein Profile

Protein Summary

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with MGAT3

  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (MGAT3)
  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a (mgat3a)
  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (mgat3)
  • mannoside acetylglucosaminyltransferase 3 (Mgat3)
  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (Mgat3)
  • 1110038J12Rik protein
  • AI848272 protein
  • GNT-III protein
  • GNT3 protein
  • mgat3 protein
  • zgc:112067 protein

Protein level used designations for MGAT3

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase , mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase , beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like , N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III , glcNAc-T III , GlcNAc-T III , N-acetylglucosaminyltransferase III , GNT-III , mannoside acetyl glucosaminyltransferase 3

GENE ID SPECIES
418013 Gallus gallus
470218 Pan troglodytes
481244 Canis lupus familiaris
520087 Bos taurus
553676 Danio rerio
703643 Macaca mulatta
100055333 Equus caballus
100090777 Ornithorhynchus anatinus
100381104 Xenopus laevis
100401747 Callithrix jacchus
100461728 Pongo abelii
100492491 Xenopus (Silurana) tropicalis
17309 Mus musculus
4248 Homo sapiens
29582 Rattus norvegicus
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