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Mediator Complex Subunit 26 Proteins (MED26)

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. Additionally we are shipping MED26 Antibodies (58) and MED26 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MED26 9441 O95402
MED26 70625 Q7TN02
Rat MED26 MED26 306328  
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Top MED26 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

MED26 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Mediator Complex Subunit 26 (MED26) Interaction Partners

Human Mediator Complex Subunit 26 (MED26) interaction partners

  1. the MED26-NTD functions as a molecular switch in the exchange of TBP-associated factor 7 (TAF7 (show TAF7 Proteins)) for LEC to facilitate the transition from initiation to elongation during transcription of a subset of snRNA genes

  2. MED26 can function as a molecular switch that interacts first with TFIID in the Pol II initiation complex and then exchanges TFIID for complexes containing ELL/EAF and P-TEFb to facilitate transition of Pol II into the elongation stage of transcription.

  3. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

  4. findings identify MED19 (show MED19 Proteins)/MED26 as a probable composite REST interface in Mediator and further clarify the mechanistic basis by which Mediator facilitates REST-imposed epigenetic restrictions on neuronal gene expression

MED26 Protein Profile

Protein Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Gene names and symbols associated with MED26

  • mediator of RNA polymerase II transcription subunit 26 (MED26)
  • cofactor required for Sp1 transcriptional activation, subunit 7 (crsp7)
  • mediator complex subunit 26 (MED26)
  • mediator complex subunit 26 (Med26)
  • mediator complex subunit 26 (med26)
  • 5730493L18Rik protein
  • AI414941 protein
  • AW495270 protein
  • crsp7 protein
  • CRSP70 protein
  • med26 protein
  • Slc35e1 protein
  • wu:fe06c07 protein
  • wu:fi75a09 protein
  • zgc:55993 protein

Protein level used designations for MED26

mediator of RNA polymerase II transcription subunit 26 , CRSP complex subunit 7 , CRSP70 , mediator complex subunit 26 , ARC70 , activator-recruited cofactor 70 kDa component , cofactor required for Sp1 transcriptional activation subunit 7 , cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) , cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa , transcriptional coactivator CRSP70 , solute carrier family 35, member E1 , CRSP70-like protein

GENE ID SPECIES
725023 Apis mellifera
406332 Danio rerio
9441 Homo sapiens
70625 Mus musculus
306328 Rattus norvegicus
399180 Xenopus laevis
506331 Bos taurus
Selected quality suppliers for MED26 Proteins (MED26)
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