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Mediator Complex Subunit 28 Proteins (MED28)

May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways (By similarity). Additionally we are shipping Mediator Complex Subunit 28 Kits (31) and Mediator Complex Subunit 28 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MED28 80306 Q9H204
MED28 305391 P68943
MED28 66999 Q920D3
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Top Mediator Complex Subunit 28 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,388.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,418.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,418.17
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
Yeast Aedes aegypti His tag   1 mg Log in to see 56 to 66 Days
$2,436.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

MED28 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

Mouse (Murine)

More Proteins for Mediator Complex Subunit 28 (MED28) Interaction Partners

Human Mediator Complex Subunit 28 (MED28) interaction partners

  1. All trans-retinoic acid can reverse the suppressive effect of MED28 on HBP1 and E-cadherin (show CDH1 Proteins) and inactivate the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway in colorectal cancer, suggesting a protective effect of ATRA against colorectal cancer.

  2. This paper describes a link between Med23 (show MED23 Proteins) and IFN-lambda3, provides evidence for the crucial role of IFN-lambda in HSV-1 immune control.

  3. These data indicate that MED28 regulates cellular migration in a MEK1 (show MAP2K1 Proteins)-dependent manner in human breast cancer cells, reinforcing the important cellular roles of MED28.

  4. High MED28 is associated with breast cancer.

  5. demonstrate an interaction between Grb2 (show GRB2 Proteins) and magicin. In addition, merlin (show NF2 Proteins) is capable of forming a ternary complex with magicin and Grb2 (show GRB2 Proteins)

  6. EG-1 is a positive stimulator of cellular proliferation, and may possibly be involved in signaling pathways involving Src (show SRC Proteins) and MAPK (show MAPK1 Proteins) activation.

  7. EG-1 may be involved in signaling pathways including c-Src activation.

  8. EG-1 has a role in breast tumor growth

  9. Study reports that down-regulation of human Med28 expression in NIH3T3 cells results in a significant induction of several genes associated with smooth muscle cell (SMC (show DYM Proteins))differentiation; conversely, overexpression of MED28 represses SMC (show DYM Proteins) gene expression.

Mouse (Murine) Mediator Complex Subunit 28 (MED28) interaction partners

  1. These findings document the essential role of Med28 in the developing embryo as well as in acquisition and maintenance of pluripotency during reprogramming.

  2. EG-1 has a role in breast tumor growth

Mediator Complex Subunit 28 (MED28) Protein Profile

Protein Summary

May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene names and symbols associated with MED28

  • mediator complex subunit 28 (MED28)
  • mediator complex subunit 28 (Med28)
  • mediator complex subunit 28 (med28)
  • mediator of RNA polymerase II transcription, subunit 28 homolog (yeast) (Med28)
  • 1500003D12Rik protein
  • AI451633 protein
  • AU045690 protein
  • Eg1 protein
  • FKSG20 protein
  • magicin protein
  • RGD1305875 protein
  • wu:fc74b11 protein
  • zgc:103633 protein

Protein level used designations for MED28

mediator of RNA polymerase II transcription, subunit 28 homolog , mediator complex subunit 28 , endothelial-derived gene 1 , endothelial-derived protein 1 , mediator of RNA polymerase II transcription subunit 28 , merlin and Grb2-interacting cytoskeletal protein , tumor angiogenesis marker EG-1 , endothelial-derived , mediator of RNA polymerase II transcription, subunit 28

GENE ID SPECIES
425350 Gallus gallus
461133 Pan troglodytes
488813 Canis lupus familiaris
80306 Homo sapiens
305391 Rattus norvegicus
513972 Bos taurus
493610 Danio rerio
101121011 Ovis aries
66999 Mus musculus
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