Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Proteins (MAGEA1)

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Additionally we are shipping Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Antibodies (124) and Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAGEA1 4100 P43355
Mouse MAGEA1 MAGEA1 17137  
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Top Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
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Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$720.00
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Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 2 to 3 Days
$595.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human GST tag   10 μg Log in to see 2 to 3 Days
$662.36
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Human Un-conjugated   10 μg Log in to see 6 Days
$921.64
Details

MAGEA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) Interaction Partners

Human Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) interaction partners

  1. Authors revealed a novel interaction between MAGEA1 and the intracellular segment of NOTCH1 receptor (NICD1). MAGEA1 reduced NICD1's stability by promoting the ubiquitin modification of NICD1.

  2. In patients with Colon cancer, the expression of MAGE (show MAGEB10 Proteins)-A(1-6) gene was associated with a poor prognosis.

  3. MAGEA1 was expression in 15% of synovial sarcomas and was not associated with prognosis.

  4. Data show that overall survival (OS) was significantly lower for patients expressing pan-MAGE (show MAGEB10 Proteins) or MAGE (show MAGEB10 Proteins)-A1/A3/A4 in both independent cohorts.

  5. These data demonstrate that MAGE (show MAGEB10 Proteins)-A1-, MAGE-A3 (show MAGEA3 Proteins)-, and NY-ESO-1 (show CTAG1B Proteins)-specific T cells with antigen-specific cytotoxicity can be cultured from healthy donors and patient-derived cells making adoptive immunotherapy with these cytotoxic T lymphocyte feasible.

  6. up-regulation of MAGE (show MAGEB10 Proteins)-A1 dramatically promoted proliferation, migration, and invasion of human melanoma cell lines in vitro

  7. The overall survival of laryngeal squamous cell carcinoma patients with positive MAGE-A1, MAGE-A9, or MAGE-A11 expression was lower than the patients without MAGE-A1, MAGE-A9, or MAGE-A11 expression.

  8. MAGE (show MAGEB10 Proteins)-A is more highly expressed than NY-ESO-1 (show CTAG1B Proteins) in a majority of human malignancies

  9. TRIM31 directly binds to NSE4, suggesting the existence of a TRIM31-MAGEA1-NSE4 complex reminiscent of the NSE1-NSE3-NSE4 trimer.

  10. Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.

Mouse (Murine) Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) interaction partners

  1. results indicate that the fusion of Hsp70 (show HSP70 Proteins) to Mage (show MAGEB10 Proteins)-a1 can enhance immune responses and anti-tumor effects against Mage (show MAGEB10 Proteins)-a1-expressing tumors

Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1) Protein Profile

Protein Summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Gene names and symbols associated with MAGEA1

  • MAGE family member A1 (MAGEA1)
  • melanoma antigen, family A, 1 (Magea1)
  • CT1.1 protein
  • Mage-a1 protein
  • MAGE1 protein

Protein level used designations for MAGEA1

MAGE-1 antigen , antigen MZ2-E , cancer/testis antigen 1.1 , cancer/testis antigen family 1, member 1 , melanoma antigen MAGE-1 , melanoma antigen family A 1 , melanoma-associated antigen 1 , melanoma-associated antigen MZ2-E , melanoma antigen family A, 1

GENE ID SPECIES
4100 Homo sapiens
17137 Mus musculus
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