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Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) Proteins (MPP4)

MPP4 encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. Additionally we are shipping MPP4 Antibodies (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MPP4 58538 Q96JB8
MPP4 227157 Q6P7F1
MPP4 58808  
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Top MPP4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,234.00
Details

MPP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) Interaction Partners

Human Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) interaction partners

  1. MPP4 gene is highly expressed in retina, but no mutations were identified in a panel of 300 unrelated patients with retinitis pigmentosa.

Mouse (Murine) Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4) interaction partners

  1. Results describe the temporal and spatial expression patterns of mouse membrane palmitoylated protein 4 (Mpp4) gene.

  2. Association of Veli3 with MPP4 suggests that the MAGUKs recruit Veli3 and its binding partners to different cellular regions of the retina where they may participate in the organization of specialized intercellular junctions.

  3. These findings suggest that Mpp4 coordinates Psd95 (show DLG4 Proteins)/Veli3 assembly and maintenance at synaptic membranes. Mpp4 is a critical recruitment factor to organize scaffolds at the photoreceptor synapse.

  4. Results show that Mpp4 organizes a presynaptic protein complex and has a role in modulating Ca(2 (show CA2 Proteins)+) homeostasis and synaptic transmission in rod photoreceptors.

  5. Data suggest that both scaffold proteins PSD95beta and MPP4 are essential for the modulation of PMCA levels at the presynaptic plasma membrane and thereby influence the photoreceptor synaptic calcium handling.

MPP4 Protein Profile

Protein Summary

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with MPP4

  • membrane protein, palmitoylated 4 (LOC784680)
  • membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) (MPP4)
  • membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) (Mpp4)
  • ALS2CR5 protein
  • Dlg6 protein

Protein level used designations for MPP4

MAGUK p55 subfamily member 4 , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein , discs large homolog 6 , discs, large homolog 6 , mDLG6 , membrane palmitoylated protein 4 , rDLG6

GENE ID SPECIES
784680 Bos taurus
58538 Homo sapiens
227157 Mus musculus
58808 Rattus norvegicus
769757 Gallus gallus
488477 Canis lupus familiaris
100626771 Sus scrofa
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