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This locus encodes a member of the methyltransferase family, and is involved in chromatin remodeling. Additionally we are shipping METTL8 Antibodies (4) and many more products for this protein.
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Data, including data from studies using mutant/knockout mice and cell lines from such mice, suggest that METTL2 (show METTL2A Proteins) and METTL6 (show METTL6 Proteins) (but not METTL8) contribute to post-transcriptional methylation of cytidine (formation of 3-methylcytidine) in tRNA; METTL2 (show METTL2A Proteins) methylates tRNA(Thr (show TRH Proteins)) and tRNA(Arg); METTL6 (show METTL6 Proteins) interacts with seryl-tRNA synthetase (show SARS Proteins) and methylates tRNA(Ser (show SIGLEC1 Proteins)); METTL8 catalyzes post-transcriptional methylation of cytidine in mRNA.
This locus encodes a member of the methyltransferase family, and is involved in chromatin remodeling. Transcripts from this locus can be induced or inhibited by cell stretch and affect cell differentiation in the myogenic or adipogenic pathways. Multiple transcript variants encoding different isoforms have been found for this gene. Additional splice variants have been described in the literature but they meet nonsense-mediated decay (NMD) criteria and are likely to be degraded as soon as they are transcribed.
methyltransferase-like protein 8
, tension-induced/inhibited protein
, tension induced/inhibited protein