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The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010].. Additionally we are shipping Mucin 6, Oligomeric Mucus/gel-Forming Antibodies (32) and Mucin 6, Oligomeric Mucus/gel-Forming Kits (13) and many more products for this protein.
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Cftr (show CFTR Proteins)-/- mice showed a higher expression of Muc6 at both protein and RNA levels compared with their control Cftr (show CFTR Proteins)+/+ littermates, suggesting that Muc6 may contribute to blocking of pancreatic acini and ducts in mouse models of cystic fibrosis (show S100A8 Proteins).
organization of the secreted gel-forming mucin (show MUC2 Proteins) gene cluster and the complete gene structure of its different members
transcription of the Mucin 6 gene in thymic medullary epithelial cells is indeed Aire (show AIRE Proteins)-dependent
outcome, while the gain of aberrant expression of MUC5AC and particularly of MUC6 was associated with favorable outcome in colorectal cancer, notably in intermediate stages II and III
In ovarian mucinous tumors, MUC6 expression changes with the progression of benign to borderline and malignant tumours
CDX2 (show CDX2 Proteins), MUC1 (show MUC1 Proteins), MUC5AC, and MUC6 expression patterns may provide better estimations of survival after surgical resection of small intestinal adenocarcinoma.
The expression of a subset of mucins (MUC2, MUC6, MUC5B) was also correlated with sialyl-Tn expression in LS174T cells.
There was no difference in the expression of deep MUC1 (show MUC1 Proteins), MUC2 (show MUC2 Proteins), MUC5AC, or MUC6 between the groups of gastric cancer and controls.
Human TTF2 (show FOXE1 Proteins) is a lectin that binds alpha-GlcNAc-capped mucin 6 g with antibiotic activity against Helicobacter pylori.
High MUC6 expression is associated with gastric carcinoma.
we report the expression pattern of MUC2 (show MUC2 Proteins), MUC5AC, MUC5B, and MUC6 in a large series of colorectal carcinomas
Data indicate that MUC1 (show MUC1 Proteins) and MUC4 (show MUC4 Proteins) were differentially glycosylated as the disease progressed, and the expression of MUC6 in acinar cells.
Secretory carcinomas of breast show a unique pattern of strong MUC2 (show MUC2 Proteins), MUC6, and MUC 4 (show MUC4 Proteins) expression.
The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993
mucin 6, gastric
, mucin 6, oligomeric mucus/gel-forming
, oligomeric mucus/gel-forming
, ovomucin, beta subunit
, ovomucin, beta-subunit
, gastric mucin-6
, gastric mucin-like protein
, secreted gel-forming mucin-6