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Mycn (MYCN) ELISA Kits

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. Additionally we are shipping MYCN Antibodies (85) and MYCN Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MYCN 4613 P04198
MYCN 298894 Q63379
MYCN 18109 P03966
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Top MYCN ELISA Kits at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 0.312-20 ng/mL   96 Tests Log in to see 11 to 13 Days
$946.00
Details
Mouse
  96 Tests Log in to see 11 to 13 Days
$946.00
Details
Chicken
  96 Tests Log in to see 11 to 13 Days
$1,095.60
Details

More ELISA Kits for MYCN Interaction Partners

Human Mycn (MYCN) interaction partners

  1. N-myc protein also could bind to the promoter of pri-miR (show MLXIP ELISA Kits)-4295 and inhibit the expression of RUNX3 (show RUNX3 ELISA Kits) in glioma cells.

  2. many of the novel findings connect directly or indirectly to regulatory pathways controlling MYCN activity, bringing the old enemy into the spotlight of our current and future targeted drug efforts

  3. Novel pharmacodynamic biomarkers for MYCN protein and PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) pathway signaling in children with neuroblastoma (show ARHGEF16 ELISA Kits).

  4. Authors describe an inverse correlation between WT1 (show WT1 ELISA Kits) gene expression and MYCN amplification and expression in neuroblastoma (show ARHGEF16 ELISA Kits) tumors.

  5. The MRN complex is essential to restrain MYCN-induced replication stress during neural cell proliferation.

  6. Oncogenic MYCN re-wires its own interaction and signalling networks to repress regulators of normal cellular developmental processes, such as differentiation.

  7. the expression of MYCN, HMGA2, and DICER1 (show DICER1 ELISA Kits) seems to be correlated to each other and the expression of the let7-genes impacted by their expression.

  8. N-Myc and activated AKT1 (show AKT1 ELISA Kits) are sufficient to transform human prostate epithelial cells to prostate adenocarcinoma and neuroendocrine carcinoma. N-Myc is required for tumor maintenance.

  9. This study strongly suggests that AT7519 is a promising drug for the treatment of high-risk neuroblastoma (show ARHGEF16 ELISA Kits) patients with MYCN amplification.

  10. the MNA (MYCN amplification)subclone appears to be constraint by the tumor environment and thus less relevant for tumor behavior in aggressive tumors with a high genomic instability and many segmental aberrations

Mouse (Murine) Mycn (MYCN) interaction partners

  1. Loss of N-myc significantly impairs the Sonic hedgehog (show SHH ELISA Kits) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (show CCND2 ELISA Kits).

  2. Study shows that ground-state embryonic stem cells express low Myc (show MYC ELISA Kits) levels. Deletion of both c-myc (show MYC ELISA Kits) and N-myc activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc (show MYC ELISA Kits)-depleted stem cells enter a state of dormancy.

  3. MYCN overexpression is not sufficient for these cells to form tumors in nude mice

  4. ITGA4 (show ITGA4 ELISA Kits) expression enhances metastasis in MYCN low neuroblastoma (show ARHGEF16 ELISA Kits).

  5. MYCN plays a critical role in expansion and survival of aggressive medulloblastoma-propagating cells.

  6. SUMOylation may be part of a quality-control mechanism acting on misfolded Myc (show MYC ELISA Kits) proteins.

  7. The results of this study provided evidence that N-myc deficiency in the olfactory epithelium progressively diminishes proliferation and neurogenesis with negative consequences at structural and cellular levels.

  8. MYCN/LIN28B/Let-7/HMGA2 pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging

  9. The above results induced by overexpression of MYCN closely resemble the main aspects of human AML (show RUNX1 ELISA Kits), suggesting that MYCN plays a role in the etiology of AML (show RUNX1 ELISA Kits).

  10. a general mechanism for p53 (show TP53 ELISA Kits) inactivation in some embryonal cell types and consequent susceptibility to MycN oncogenesis at the point of embryonal tumor initiation

MYCN Antigen Profile

Antigen Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Gene names and symbols associated with Mycn (MYCN) ELISA Kits

  • olfactory receptor, family 8, subfamily S, member 1-like (LOC515887) antibody
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) antibody
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (Mycn) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (MYCN) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN) antibody
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (Mycn) antibody
  • bHLHe37 antibody
  • c-nmyc antibody
  • MODED antibody
  • MYCNOT antibody
  • N-myc antibody
  • Nmuc1 antibody
  • Nmyc antibody
  • Nmyc-1 antibody
  • Nmyc1 antibody
  • ODED antibody

Protein level used designations for Mycn (MYCN) ELISA Kits

N-myc proto-oncogene protein , class E basic helix-loop-helix protein 37 , neuroblastoma MYC oncogene , neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene , oncogene NMYC , pp65/67 , v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived , Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc) , Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc) , N-myc protein , neuroblastoma myc-related oncogene 1

GENE ID SPECIES
515887 Bos taurus
4613 Homo sapiens
298894 Rattus norvegicus
421948 Gallus gallus
482978 Canis lupus familiaris
18109 Mus musculus
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