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Myelin Protein Zero-Like 2 Proteins (MPZL2)

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Additionally we are shipping MPZL2 Antibodies (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MPZL2 10205 O60487
MPZL2 14012  
Rat MPZL2 MPZL2 300679  
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Top MPZL2 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,256.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,262.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MPZL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Myelin Protein Zero-Like 2 (MPZL2) Interaction Partners

Human Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. CLCA2 (show CLCA2 Proteins) links junctional adhesion molecule (show AMICA1 Proteins) EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation.

  2. Findings highlight Eva1 as a novel regulator of GIC function and also provide new mechanistic insight into the role of noncanonical NF-kappaB (show NFKB1 Proteins) activation in GIC.

  3. EVA (show SLC26A4 Proteins) is expressed in human choroid plexus epithelial cells and CD4 (show CD4 Proteins) T lymphocytes and regulates CD4 (show CD4 Proteins)+ T lymphocyte adhesion to human choroid plexus epithelial cells in vitro. These data suggest a novel mechanism to regulate CNS immune surveillance.

Mouse (Murine) Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. EVA deficiency results in increased experimental autoimmune encephalomyelitis disease severity. EVA-knockout Mice have normal immune system development and choroid plexus morphology.

  2. modulation of Eva1 expression in thymocytes is crucial for lymphocyte physiological developmental progression and stromal differentiation

  3. These results suggest that EVA expressed in choroid plexus cells may regulate the permeability of the blood-CSF (show CSF2 Proteins) barrier.

MPZL2 Protein Profile

Protein Summary

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain\; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MPZL2

  • myelin protein zero-like 2b (mpzl2b)
  • myelin protein zero-like 2 (MPZL2)
  • myelin protein zero-like 2 (Mpzl2)
  • cb837 protein
  • Eva protein
  • Eva1 protein
  • mpzl2 protein
  • wu:fb07b02 protein

Protein level used designations for MPZL2

epithelial V-like antigen 1 , myelin protein zero-like 2 , myelin protein zero-like protein 2

GENE ID SPECIES
336830 Danio rerio
419779 Gallus gallus
699330 Macaca mulatta
10205 Homo sapiens
14012 Mus musculus
300679 Rattus norvegicus
540423 Bos taurus
489384 Canis lupus familiaris
100172793 Pongo abelii
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