Myopalladin Proteins (MYPN)

Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Additionally we are shipping Myopalladin Antibodies (39) and Myopalladin Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MYPN 84665 Q86TC9
MYPN 68802 Q5DTJ9
Rat MYPN MYPN 309760  
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Top Myopalladin Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human S tag,His tag   100 μg Log in to see 15 to 18 Days
$704.00
Details

MYPN Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

More Proteins for Myopalladin (MYPN) Interaction Partners

Human Myopalladin (MYPN) interaction partners

  1. Targeted sequencing revealed trigenic mutations: c.700G>A/p.E234K in DES (show DES Proteins), c.2966G>A/p.R989H in MYPN, and c.5918G>C/p.R1973P in CACNA1C (show CACNA1C Proteins) in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome.

  2. Homozygous truncating mutations in MYPN in 2 unrelated families with a slowly progressive congenital cap myopathy.

  3. results suggest that MYPN screening should be considered in individuals with mild nemaline myopathy, especially when cardiac problems or intranuclear rods are present

  4. Heterozygote Mypn(WT/Q526X) knock-in mice develop RCM (show Unc5c Proteins) due to persistence of mutant Mypn(Q526X) protein in the nucleus.

  5. the clinical significance of myopalladin for the functional integrity of the sarcomeric apparatus and the protection against dilated cardiomyopathy

  6. Two nonsense and 13 missense MYPN variants were identified in subjects with hypertrophic, dilated and/or restrictive cardiomyopathy.

  7. mutations in PDLIM3 (show PDLIM3 Proteins) and MYPN are infrequent in hypertrophic cardiomyopathies

  8. myopalladin plays a signaling role in targeting and orienting nebulin during sarcomere assembly

  9. myopalladin gene is a new gene associated with dilated cardiomyopathy and observed mutations in 3-4% of cases in a population. of European descent.

Pig (Porcine) Myopalladin (MYPN) interaction partners

  1. Two polymorphisms previously identified and described in the 3'UTR of MYPN and TTN (show TTN Proteins) genes in a group of Italian Large White (ILW) and Italian Duroc (ID) pigs, were analysed.

Myopalladin (MYPN) Protein Profile

Protein Summary

Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Myopalladin Proteins (MYPN)

  • myopalladin (LOC100220622)
  • myopalladin (LOC100348592)
  • myopalladin (MYPN)
  • myopalladin (mypn)
  • myopalladin (Mypn)
  • 1110056A04Rik protein
  • 9830112J03 protein
  • AI853556 protein
  • CMD1DD protein
  • CMH22 protein
  • mKIAA4170 protein
  • MYOP protein
  • RCM4 protein

Protein level used designations for Myopalladin Proteins (MYPN)

myopalladin , sarcomeric protein myopalladin, 145 kDa (MYOP)

GENE ID SPECIES
100220622 Taeniopygia guttata
100348592 Oryctolagus cuniculus
100479463 Ailuropoda melanoleuca
100495211 Xenopus (Silurana) tropicalis
100540545 Meleagris gallopavo
100564401 Anolis carolinensis
100603610 Nomascus leucogenys
84665 Homo sapiens
68802 Mus musculus
309760 Rattus norvegicus
423684 Gallus gallus
489013 Canis lupus familiaris
100624901 Sus scrofa
527123 Bos taurus
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