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Myosin IIIA Proteins (MYO3A)

The protein encoded by MYO3A belongs to the myosin superfamily. Additionally we are shipping MYO3A Antibodies (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat MYO3A MYO3A 498806  
MYO3A 53904 Q8NEV4
MYO3A 667663  
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Top MYO3A Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days

MYO3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Myosin IIIA (MYO3A) Interaction Partners

Zebrafish Myosin IIIA (MYO3A) interaction partners

  1. Data show that myo3a is localized in actin-rich ellipsoids of fish cones.

Human Myosin IIIA (MYO3A) interaction partners

  1. Study reports an amino acid substitution in MYO3A motor-head domain disrupting its ATPase activity that can cause autosomal dominant progressive hereditary hearing loss. Also, these results uncovered a novel interaction between MYO3A and PCDH15 (show PCDH15 Proteins) shedding new light on the function of myosin IIIA at stereocilia tips.

  2. Data suggest that, in enterocytes, MYO3A autophosphorylation of kinase domain at Thr184/Thr188 regulates kinase activity, translocation of MYO3A to tips of microvilli, and stability of actin cytoskeleton.

  3. The differential regulation of the kinase and motor activities allows for MYO3A to precisely self-regulate its concentration in the actin bundle-based structures of cells.

  4. Results suggest that Myo3A motor activity is regulated through a mechanism involving concentration-dependent autophosphorylation.

  5. behavioral inhibition-associated SNPs appear to be associated with differences in MYO3A- but not GAD2 (show GAD2 Proteins) lymphoblastoid-mRNA expression levels

  6. mutation in humans causes progressive nonsyndromic hearing loss DFNB30

  7. class III myosin is an actin-based motor protein having a protein kinase activity

  8. myosin IIIA can spend a majority of its ATP hydrolysis cycling time on actin

  9. the actomyosin-ADP state may be important for the ability of myosin III to function as a cellular transporter and actin cross-linker in the actin bundles of sensory cells

  10. A model in which the activity and concentration of myosin IIIA localized to the tips of actin bundles mediates the morphology of the tips in sensory cells.

Mouse (Murine) Myosin IIIA (MYO3A) interaction partners

  1. The phenotype of the Myo3a knockout mice parallels the phenotype of human DFNB30.

MYO3A Protein Profile

Protein Summary

The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.

Gene names and symbols associated with Myosin IIIA Proteins (MYO3A)

  • myosin IIIA (myo3a)
  • myosin IIIA (MYO3A)
  • myosin IIIA (Myo3a)
  • myosin IIIA (CpipJ_CPIJ005840)
  • 9030416P08Rik protein
  • DFNB30 protein
  • MYO3A protein
  • RGD1560083 protein

Protein level used designations for Myosin IIIA Proteins (MYO3A)

myosin-IIIa , myosin IIIA , myosin-IIIa-like

402814 Danio rerio
420494 Gallus gallus
450359 Pan troglodytes
487106 Canis lupus familiaris
498806 Rattus norvegicus
535824 Bos taurus
707165 Macaca mulatta
6038014 Culex quinquefasciatus
100407807 Callithrix jacchus
100467620 Ailuropoda melanoleuca
100542476 Meleagris gallopavo
100565835 Anolis carolinensis
100597781 Nomascus leucogenys
53904 Homo sapiens
667663 Mus musculus
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