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NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001 [PubMed 11594753]).[supplied by OMIM, Mar 2008].. Additionally we are shipping NAD Kinase Antibodies (30) and NAD Kinase Proteins (15) and many more products for this protein.
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Data indicate metabolic enzymes NAD kinase and ketohexokinase (show KHK ELISA Kits) as candidate metabolic gene targets, and the chromatin remodeling protein INO80C (show INO80C ELISA Kits) as a tumor suppressor in KRAS(MUT (show MUT ELISA Kits)) colorectal tumor xenograft.
Depletion of wild-type NADK in pancreatic ductal adenocarcinoma cells attenuates cancer cell growth.
Taken together, this indicates that Ser (show SIGLEC1 ELISA Kits)-188 (and perhaps the other residues) is an important phosphorylation site that can downregulate the NAD kinase activity of this critical enzyme.
Using purified human NAD kinase, we revealed a sigmoidal kinetic behavior toward ATP and the inhibitory effects of NADPH and NADH
NAD kinase levels control the NADPH concentration in human cells
NADK catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions (Lerner et al., 2001
Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase)
, poly(P)/ATP NAD kinase