anti-NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Antibodies

The protein encoded by NEK6 is a kinase required for progression through the metaphase portion of mitosis. Additionally we are shipping NEK6 Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEK6 59126 Q9ES70
NEK6 10783 Q9HC98
NEK6 360161 P59895
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Top anti-NEK6 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of NEK6 (arrow) using rabbit polyclonal NEK6 Antibody (N-term) (ABIN1882104) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NEK6 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Nek6 (arrow) using rabbit polyclonal Mouse Nek6 Antibody (C-term) (ABIN657847). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Nek6 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-NEK6mouse monoclonal antibody. (ABIN2452601, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-NEK6mouse monoclonal antibody. (ABIN2452601, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-NEK6 mouse monoclonal antibody. (ABIN2452617, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-NEK6mouse monoclonal antibody. (ABIN2452617, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IP, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-NEK6 mouse monoclonal antibody. (ABIN2452655, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-NEK6mouse monoclonal antibody. (ABIN2452655, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: NEK6 Antibody (5D7) [NBP1-47865] - Staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NEK6 mouse monoclonal antibody. Immunohistochemistry-Paraffin: NEK6 Antibody (5D7) [NBP1-47865] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-NEK6 mouse monoclonal antibody. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: NEK6 Antibody [NLS7305] - Analysis of anti-NEK6 antibody with human brain, Purkinje neurons at 13 ug/ml. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details

NEK6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NEK6 Antibodies

  1. Human Polyclonal NEK6 Primary Antibody for WB - ABIN1882104 : Belham, Roig, Caldwell, Aoyama, Kemp, Comb, Avruch: A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for 1882104

  2. Cow (Bovine) Polyclonal NEK6 Primary Antibody for WB - ABIN2773927 : Lee, Hyun, Chun, Kang: Human NIMA-related kinase 6 is one of the Fe65 WW domain binding proteins. in Biochemical and biophysical research communications 2007 (PubMed)

More Antibodies against NEK6 Interaction Partners

Mouse (Murine) NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) interaction partners

  1. NEK6 is overexpressed in various human cancer tissues, and ectopic expression of NEK6 increases tumor promoter-induced transformation of JB6 Cl41 mouse epidermal cells.

  2. During early embryogenesis nek6 is highly expressed in primary giant trophoblast cells. Later in embryogenesis, nek6 is found in ventricular and sub-ventricular regions.

Arabidopsis thaliana NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) interaction partners

  1. NEK6 (show NEK5 Antibodies) forms heterodimers with NEK4 and NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of beta-tubulins.

Human NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) interaction partners

  1. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7 (show NEK7 Antibodies), and Nek9 (show NEK9 Antibodies) is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 (show KIF20A Antibodies) and Kif14 (show KIF14 Antibodies) to properly coordinate cytokinesis.

  2. our studies establish NEK6 signaling as a central mechanism mediating castration-resistant prostate cancer

  3. overexpression of PAK1 (show PAK1 Antibodies), NEK6, AURKA (show AURKA Antibodies), and AURKB (show AURKB Antibodies) genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

  4. We found that NEK6-mediated phosphorylation of TPP1 (show TPP1 Antibodies) Ser255 in G2/M phase regulates the association between telomerase activity and TPP1 (show TPP1 Antibodies). Furthermore, we found evidence that POT1 (show POT1 Antibodies) negatively regulates TPP1 (show TPP1 Antibodies) phosphorylation because the level of Ser255 phosphorylation was elevated when telomeres were elongated by a POT1 (show POT1 Antibodies) mutant lacking its OB-fold domains

  5. Overexpression of AURKA (show AURKA Antibodies) and NEK6 genes was significantly more pronounced in Ulcerative colitis patients with more extensive colon involvement

  6. NEK6 suppresses the cell growth arrest induced by TGFbeta (show TGFB1 Antibodies). Mechanically, NEK6 blocks nuclear translocation of Smad4 (show SMAD4 Antibodies), which is essential for TGFbeta (show TGFB1 Antibodies) function.

  7. Nek6 is also a critical signaling molecule that helps prevent cardiac hypertrophy and inhibits the Akt (show AKT1 Antibodies) signaling pathway.

  8. Nek6 facilitates association of Hsp72 (show HSPA1A Antibodies) with the mitotic spindle, where it promotes stable K-fiber assembly through recruitment of the ch-TOG (show CKAP5 Antibodies)-TACC3 (show TACC3 Antibodies) complex.

  9. Nek6 plays an important role in the premature senescence of cancer cells.

  10. High Nek6 is associated with hepatic cell cancer.

NEK6 Antigen Profile

Protein Summary

The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene names and symbols associated with NEK6

  • NIMA (never in mitosis gene a)-related expressed kinase 6 (Nek6) antibody
  • NIMA (never in mitosis gene a)-related kinase 6 (nek6) antibody
  • NIMA (never in mitosis gene a)-related kinase 6 (NEK6) antibody
  • NIMA-related kinase 5 (NEK5) antibody
  • NIMA-related kinase 6 (NEK6) antibody
  • NIMA-related kinase 6 (nek6) antibody
  • NIMA-related kinase 6 (Nek6) antibody
  • 1300007C09Rik antibody
  • ATNEK5 antibody
  • MOE17.17 antibody
  • NIMA-related kinase 5 antibody
  • NIMA-RELATED KINASE5 antibody
  • si:ch211-167p9.4 antibody
  • SID6-1512 antibody

Protein level used designations for NEK6

NIMA-related expressed kinase 6 , never in mitosis A-related kinase 6 , nimA-related protein kinase 6 , serine/threonine-protein kinase Nek6 , putative serine-threonine protein kinase , NIMA (never in mitosis gene a)-related kinase 6 , protein kinase SID6-1512 , NIMA (never in mitosis gene a)-related expressed kinase 6

GENE ID SPECIES
59126 Mus musculus
497165 Danio rerio
417101 Gallus gallus
609003 Canis lupus familiaris
100514624 Sus scrofa
515816 Bos taurus
821634 Arabidopsis thaliana
10783 Homo sapiens
380346 Xenopus laevis
360161 Rattus norvegicus
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