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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Neurofilament, Heavy Polypeptide Kits (39) and Neurofilament, Heavy Polypeptide Proteins (8) and many more products for this protein.
Showing 10 out of 448 products:
Human Monoclonal NEFH Primary Antibody for ELISA (Capture), EIA - ABIN614809
Côté, Collard, Julien: Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. in Cell 1993
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Human Monoclonal NEFH Primary Antibody for WB - ABIN393231
Shrestha, Irvin, Taylor, Wiener, Pajewski, Haritunians, Delaney, Schambelan, Polak, Arnett, Chen, Grunfeld: A genome-wide association study of carotid atherosclerosis in HIV-infected men. in AIDS 2010
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Chicken Monoclonal NEFH Primary Antibody for IHC (fro), IF - ABIN112360
Bauwens, De Groot, Ramaekers, Veldman, Huizing: Expression of intermediate filament proteins in the adult human vestibular labyrinth. in The Annals of otology, rhinology, and laryngology 1992
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Bird (Avian) Monoclonal NEFH Primary Antibody for IHC (p), IHC - ABIN152482
Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992
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Human Monoclonal NEFH Primary Antibody for IHC (fro), IHC (p) - ABIN1108414
Lees, Shneidman, Skuntz, Carden, Lazzarini: The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. in The EMBO journal 1988
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Human Polyclonal NEFH Primary Antibody for IF (p), IHC (p) - ABIN2177936
Liu, Nie, Zhao, Zhang, Zhang, Wang, Cheng: Conserved dopamine neurotrophic factor-transduced mesenchymal stem cells promote axon regeneration and functional recovery of injured sciatic nerve. in PLoS ONE 2014
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Cow (Bovine) Monoclonal NEFH Primary Antibody for ICC, IF - ABIN269048
van der Kallen, Eggers, Ehlert, Verhaagen, Smit, van Kesteren: Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. in PLoS ONE 2015
All Species Monoclonal NEFH Primary Antibody for EIA, IHC (fro) - ABIN111967
Lukás, Dráber, Bucek, Dráberová, Viklický, Dolezel: Expression of phosphorylated high molecular weight neurofilament protein (NF-H) and vimentin in human developing dorsal root ganglia and spinal cord. in Histochemistry 1994
Microgravity causes substantial down-regulation of nerve tissue proteins, choline acetyltransferase, NF200, and calbindin (show CALB1 Antibodies) in mouse motor neurons.
Data conclude that NF-H and NF-M (show CEBPB Antibodies) C-terminal domains do not normally regulate NF transport rates as previously proposed, but instead increase the proteolytic resistance of NF, thereby stabilizing the stationary neurofilament cytoskeleton along axons.
plasma NfH levels closely reflect later stages of disease progression and therapeutic response in the SOD1 (show SOD1 Antibodies)(G93A) mouse model of amyotrophic lateral sclerosis
NFH expression reveals an exquisite level of Cb stripe complexity that respects the transverse zone divisions and delineates an intricately patterned target field for Cb afferents.
results obtained in mouse model for leprous neuropathy indicate biochemical alterations in neurofilaments, i.e., hyperphosphorylation of NF-H and NF-M (show CEBPB Antibodies)
Overexpression of peripherin (show PRPH Antibodies) in mice deficient for neurofilament light (NF-L (show NEFL Antibodies)) subunits induced a progressive ALS-like spinal motor neuron degeneration (show CLN8 Antibodies) prevented by simultaneous overexpression of NF-H
NF-H regulates the association of NFs with kinesin. Phosphorylation of NF-H dissociates NFs from kinesin and provides a mechanism by which NF-H phosphorylation can contribute to the slowing of NF axonal transport.
Alpha-internexin (show INA Antibodies) coassembles with all 3 neurofilament proteins into a single network of filaments in quadruple-transfected cells. Deleting NF-M (show CEBPB Antibodies) alone or together with NF-H in mice reduces alpha-internexin (show INA Antibodies) transport & content in axons throughout the CNS.
We have validated the serum pNF-H assay as an unbiased measurement of axonal injury in EAE, facilitating rapid screening of potential neuroprotective therapies in this model.
RE1 silencing transcription factor (show REST Antibodies) (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin (show INA Antibodies), NF-H and NF-M (show CEBPB Antibodies) genes
data support the use of Cebrospinal fluid phosphorylated NFH as a prognostic biomarker for amyotrophic lateral sclerosis.
Study found a significant correlation between values of 8-hydroxy-2'-deoxyguanosine and phosphorylated NF-H only in clinically isolated syndrome group. While the plasma values of 8-hydroxy-2'-deoxyguanosine reflect the degree of acute demyelination in clinically isolated syndrome, phosphorylated NF-H values reflect that in relapsing-remitting multiple sclerosis.
Results provide evidence that in particular pNfH can be used as a good diagnostic biomarker of ALS (show IGFALS Antibodies) at the diagnostic stage. Moreover, results indicate that NfL (show NEFL Antibodies) may be useful in monitoring disease progression in a subset of patients.
Level of neurofilament heavy chain and light chains were significantly elevated in the cerebrospinal fluid of Amyotrophic Lateral Sclerosis (ALS) patients compared to healthy controls/controls without parenchymal central nervous system involvement and ALS mimic disease patients.
Study found a significant increase of pNF-H levels in both plasma and CSF (show CSF2 Antibodies) in amyotrophic lateral sclerosis patients
Studied diagnostic Value of Serum Levels of GFAP (show GFAP Antibodies), pNF-H, and NSE (show ENO2 Antibodies) Compared With Clinical Findings in Severity Assessment of Human Traumatic Spinal Cord Injury.
This study demonstrated that Higher NF-L (show NEFL Antibodies) concentrations (beta = -0.26) were associated with functional decline in patients with vascular burden.
Phospho-NFH levels were significantly higher in amyotrophic lateral sclerosis patients in comparison with controls, in particular in fast progressors.
Data identified NEFH methylation as a candidate epigenetic marker for prognosis of RCC patients as well as prediction of anti-vascular endothelial growth factor-based therapy response.
Subconcussive repetitive trauma in amateur boxing causes a mild traumatic brain injury that may be diagnosed by CSF (show CSF2 Antibodies) analysis of expressed pNFH, even without unconsciousness or concussion symptoms.
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
neurofilament heavy polypeptide
, 200 kDa neurofilament protein
, neurofilament 200kDa
, neurofilament triplet H protein
, neurofilament, heavy polypeptide 200kDa
, neurofilament, heavy polypeptide
, neurofilament, heavy polypeptide 200kDa-like
, heavy neurofilament protein
, intermediate filament protein