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Neurogenin 2 Proteins (NEUROG2)

NEUROG2 encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. Additionally we are shipping Neurogenin 2 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEUROG2 63973 Q9H2A3
NEUROG2 11924 P70447
Rat NEUROG2 NEUROG2 295475  
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Top Neurogenin 2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

NEUROG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Neurogenin 2 (NEUROG2) Interaction Partners

Xenopus laevis Neurogenin 2 (NEUROG2) interaction partners

  1. Phosphorylation of Ngn2 occurs in both the N- and C-terminal regions, either side of the conserved basic Helix-Loop-Helix domain.

  2. NeuroD (show NEUROD1 Proteins) promoter is substantially more sensitive to the phosphorylation status of Ngn2 than the Delta promoter, and that this can be attributed to differences in the ease of promoter activation.

  3. multi-site cdk (show CDK4 Proteins)-dependent phosphorylation of Ngn2 interprets cdk (show CDK4 Proteins) levels to control neuronal differentiation in response to cell cycle lengthening during development

  4. XNgnr1 positively regulates early neural cell death

  5. Data demonstrate that Neurogenin and NeuroD preferentially recognize neurogenesis-related targets through an enhancer signature of clustered consensus-binding sites and regulate neurogenesis by activating a core set of transcription factors.

Human Neurogenin 2 (NEUROG2) interaction partners

  1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells.

  2. Results show that neurogenin-1 (show NEUROG1 Proteins) and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media.

  3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury

  4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD.

  5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells.

  6. Rat and mouse species-dependent differences of Nurr1 (show NR4A2 Proteins) and Ngn2 actions in dopamine neuron differentiation.

Mouse (Murine) Neurogenin 2 (NEUROG2) interaction partners

  1. data suggest that common reprogramming mechanisms exist driving the conversion of lineage-distant somatic cell types to neurons and reveal a critical role for CEND1 (show CEND1 Proteins) in NEUROG2-driven astrocytic reprogramming.

  2. Findings suggest the strict spatio-temporal expression of Notch (show NOTCH1 Proteins) effector genes plays an important role during hippocampal neurogenesis and suggests that Notch1 (show NOTCH1 Proteins), Hes1 and Ngn2 were regulated by changing some specific CpG sites of their promoters.

  3. IFN-gamma (show IFNG Proteins) inhibits neuronal differentiation of neural progenitor cells by negatively regulating the expression of Neurog2 via the JAK (show JAK3 Proteins)/STAT1 (show STAT1 Proteins) pathway.

  4. In mid-embryonic neocortical walls, expression of Neurog2-d4Venus mostly overlapped with that of Neurog2 protein, with a slightly (1 h) delayed onset.

  5. APP (show APP Proteins)-stimulated neuronal differentiation of NSPCs is mediated by Ngn2

  6. Notch (show NOTCH1 Proteins) signaling controls the overall tempo of retinogenesis through Atoh7 (show ATOH7 Proteins) and Neurog2, by integrating cell fate specification, the wave of neurogenesis and the developmental status of cells ahead of this wave

  7. Neurog1 (show NEUROG1 Proteins) and Neurog2 have unique and redundant functions in the piriform cortex, controlling the timing of differentiation of neurons

  8. Neurog2 functions as a transcriptional activator to initiate the expression of several genetic off-switches, each of which repress distinct gene expression programs during neocortical development.

  9. Sustained vs. oscillating expressions of Ngn2, Dll1 and Hes1: a model of neural differentiation of embryonic telencephalon.

  10. Neurog1 (show NEUROG1 Proteins)/2 together coordinate development of the olfactory system, which depends on tissue interactions between the olfactory bulb and epithelium.

Neurogenin 2 (NEUROG2) Protein Profile

Protein Summary

This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons.

Gene names and symbols associated with Neurogenin 2 Proteins (NEUROG2)

  • neurogenin 2 (neurog2-a)
  • neurogenin 2 (neurog2-b)
  • neurogenin 2 (NEUROG2)
  • neurogenin 2 (LOC100220670)
  • neurogenin 2 (Neurog2)
  • Atoh4 protein
  • bHLHa8 protein
  • Math4A protein
  • NEUROG2 protein
  • neurogenin-2 protein
  • ngn-2 protein
  • Ngn2 protein
  • NGN2/ATH4A protein
  • Ngnr-1 protein
  • Ngnr1 protein
  • X-ngnr-1 protein
  • x-ngnr-1a protein
  • x-ngnr-1b protein
  • Xngnr-1 protein
  • XNgnr1 protein

Protein level used designations for Neurogenin 2 Proteins (NEUROG2)

neurogenin 2 , neurogenin-2 , neurogenin-related-1 , neurogenin-related 1a , neurogenin-related 1b , class A basic helix-loop-helix protein 8 , protein atonal homolog 4 , atonal homolog 4 , helix-loop-helix protein mATH-4A , atonal-like protein 4a

GENE ID SPECIES
398061 Xenopus laevis
398062 Xenopus laevis
610724 Canis lupus familiaris
738162 Pan troglodytes
100220670 Taeniopygia guttata
63973 Homo sapiens
11924 Mus musculus
295475 Rattus norvegicus
100683455 Canis lupus familiaris
395577 Gallus gallus
615555 Bos taurus
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