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Neuromedin U Proteins (NMU)

may induce uterine smooth muscle contraction and selective vasoconstriction [RGD, Feb 2006].. Additionally we are shipping Neuromedin U Antibodies (65) and Neuromedin U Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NMU 63887 P12760
NMU 10874 P48645
Mouse NMU NMU 56183 Q9QXK8
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Top Neuromedin U Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days

NMU Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)


More Proteins for Neuromedin U (NMU) Interaction Partners

Zebrafish Neuromedin U (NMU) interaction partners

  1. These results reveal an unexpected functional and anatomical interface between the Nmu system and brainstem arousal systems that represents a novel wake-promoting pathway.

Human Neuromedin U (NMU) interaction partners

  1. our results defined NmU as a candidate drug response biomarker for HER2 (show ERBB2 Proteins)-overexpressing cancers and as a candidate therapeutic target to limit metastatic progression and improve the efficacy of HER-targeted drugs.

  2. a role for NMU gene through interaction with ADRB2 (show ADRB2 Proteins) gene in bone strength regulation

  3. Inactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells.

  4. [review] Taken together with its vascular actions, NMU may be a functional link between energy balance and the cardiovascular system and may provide a future target for therapies directed against the disorders that comprise metabolic syndrome.

  5. These results suggest that NMU plays a role in feeding behavior and catabolic functions via corticotropin-releasing hormone (show CRH Proteins).

  6. NmU expression is related to Myb (show MYB Proteins) and that the NmU/NMU1R (show NMUR1 Proteins) axis constitutes a previously unknown growth-promoting autocrine loop in myeloid leukemia (show BCL11A Proteins) cells

  7. irreversible binding of NmU to its receptors

  8. Overexpression of neuromedin U is associated with bladder tumor formation, lung metastasis and cancer cachexia

  9. Amino acid variants in NMU associate with overweight and obesity, suggesting that NMU is involved in energy regulation in humans.

  10. NMU & its cancer-specific receptors, as well as its target genes, are frequently overexpressed in clinical samples of lung cancer and in cell lines, and that those gene products play indispensable roles in the growth and progression of lung cancer cells.

Mouse (Murine) Neuromedin U (NMU) interaction partners

  1. These results suggest that NMU and NMS are involved in thermoregulation via the prostaglandin E2 and beta3 adrenergic receptors, but that endogenous NMS might play a more predominant role than NMU.

  2. the anorectic effect of the lipidated NMU is partly mediated by a decrease in gastric emptying which is subject to tachyphylaxis after continuous dosing.

  3. Beta-adrenergic and cholinergic mechanisms are involved in the anxiolytic action of neuromedin-U.

  4. Data show that neuromedin U (NMU)-deficient mice developed less severe arthritis than control mice.

  5. investigation of neuromedin U effects on factors associated with obesity/diabetes: NMU reduced food consumption/body weight; NMU increased body temperature/metabolic rate; NMU improved glucose tolerance; these effects seem to be mediated by NMUR1 (show NMUR1 Proteins)

  6. Analysis of NMU expression in ob/ob mice revealed elevated NMU mRNA levels in the dorsomedial hypothalamic (DMH (show DST Proteins)) nucleus of ob/ob mice compared to lean litter-mates. NMU mRNA levels were elevated in the DMH (show DST Proteins) of mice fasted for 24 h relative to controls

  7. results suggest that endogenous NMU may be involved in reflexes and adaptation to environmental stimuli

  8. NMU plays an important role in the regulation of feeding behavior and energy metabolism independent of the leptin (show LEP Proteins) signaling pathway.

  9. NMU receptor antagonists could be novel targets for pharmacological inhibition of allergic inflammatory diseases, including asthma.

  10. data suggest that LPS (show TLR4 Proteins)-induced IL-6 (show IL6 Proteins) expression is partly dependent on autocrine/paracrine activation of the NMU-NMU-R1 (show NMUR1 Proteins) signals in macrophages

Neuromedin U (NMU) Protein Profile

Protein Summary

may induce uterine smooth muscle contraction and selective vasoconstriction

Gene names and symbols associated with Neuromedin U Proteins (NMU)

  • neuromedin U receptor 2 (NMUR2)
  • neuromedin U (nmu)
  • neuromedin U (NMU)
  • neuromedin U (Nmu)
  • neuromedin-U-like (LOC100523263)
  • NMU protein
  • NmU-25 protein
  • si:rp71-4m17.1 protein

Protein level used designations for Neuromedin U Proteins (NMU)

NMU-R2 , neuromedin-U receptor 2 , neuromedin U , neuromedin-U , neuromedin-U-25 , prepro-NMU

100728713 Bos taurus
407657 Danio rerio
737254 Pan troglodytes
782109 Bos taurus
422748 Gallus gallus
63887 Rattus norvegicus
10874 Homo sapiens
56183 Mus musculus
611347 Canis lupus familiaris
100523263 Sus scrofa
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