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NAV1 belongs to the neuron navigator family and is expressed predominantly in the nervous system. Additionally we are shipping and many more products for this protein.
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in macaque and human retinae, we show that NaV1.1 (show SCN1A Antibodies) is concentrated in an axon initial segment (AIS (show AR Antibodies))-like region of magnocellular pathway bipolar cells, a specialization not seen in transient bipolar cells of other vertebrates
NAV1 forms a complex with the RhoGEF TRIO and the +TIP EB1 on the plus ends of growing microtubules, and regulates TRIO-mediated Rac1 activation and neurite outgrowth.
cloning of the gene neuron navigator-1 (NAV1), a human homolog of unc-53, a gene involved in axon guidance in Caenorhabditis elegans
This is the first functional characterization of the mouse homologue, mouse neuron navigator 1 (mNAV1), whose expression is largely restricted to the nervous system during development; mNAV1 associates with microtubules.
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
neuron navigator 1
, neuron navigator-1
, pore membrane and/or filament interacting like protein 3
, pore membrane and/or filament-interacting-like protein 3
, unc-53 homolog 1