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glycosylphosphatidylinositol-anchored cell adhesion protein [RGD, Feb 2006].. Additionally we are shipping NEGR1 Proteins (7) and NEGR1 Kits (6) and many more products for this protein.
Showing 10 out of 42 products:
We observed novel selection signals in CDKAL1 (show CDKAL1 Antibodies) and NEGR1, well-known diabetes and obesity susceptibility genes
NEGR1 could be an important locus influencing certain personality dimensions in BN patients.
First study to find an association between an obesity risk gene and differences in white matter integrity. As our subjects were young and healthy, our results suggest that NEGR1 has effects on brain structure independent of its effect on obesity.
Data indicate strong associations with severe obesity for single nucleotide polymorphism (SNP) rs9939609 within the FTO (show FTO Antibodies) gene and SNP rs2815752 near the NEGR1 gene.
Results imply a regulatory role for TMEM18 (show TMM18 Antibodies), BDNF (show BDNF Antibodies), MTCH2 (show MTCH2 Antibodies) and NEGR1 in adipocyte differentiation and biology. In addition, we show a variation of MAF (show MAF Antibodies) expression during adipogenesis, while NPC1 (show NPC1 Antibodies), PTER (show PTER Antibodies) and SH2B1 (show SH2B1 Antibodies) were not regulated.
Our study supports earlier reports of SH2B1 (show SH2B1 Antibodies) to be of importance in insulin (show INS Antibodies) sensitivity and, in addition, suggests potential roles of NEGR1 and MTCH2 (show MTCH2 Antibodies).
Meta-analysis of 4992 subjects revealed seven SNPs near four loci, including NEGR1, TMEM18 (show TMM18 Antibodies), SH2B1 (show SH2B1 Antibodies) /ATP2A1 (show ATP2A1 Antibodies) and MC4R (show MC4R Antibodies), showing significant association at 0.005
Gene-treatment interactions were observed for long-term (NEGR1 rs2815752, Pmetformin*SNP = 0.028; FTO (show FTO Antibodies) rs9939609, Plifestyle*SNP = 0.044) weight loss.
Data suggest that in addition to its reported role in the brain, NEGR1 is also expressed in subcutaneous adipose tissue and acts as a central 'hub' in an obesity-related transcript network.
The results of these studies provide supporting evidence for MYEOV and NEGR1 as gene targets of 11q13 gains and 1p31 deletions in a neuroblastoma (show ARHGEF16 Antibodies) subset.
The long non-coding RNA, BC048612, and microRNA-203 were determined to be positive and negative regulators of Negr1 gene expression respectively.
Negr1 controls the development of neurite arborization in vitro and in vivo.
a role of NEGR1 in the control of body weight and food intake
These results suggest a function for neurotractin/kilon as a trans-neural growth-promoting factor for outgrowing axons following hippocampal denervation.
glycosylphosphatidylinositol-anchored cell adhesion protein
neuronal growth regulator 1
, neuronal growth regulator 1-like
, IgLON family member 4
, a kindred of IgLON
, kindred of IgLON
, kilon protein