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NPSR1 is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Additionally we are shipping NPSR1 Antibodies (55) and NPSR1 Kits (8) and many more products for this protein.
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Study demonstrated that NPS (show NPS Proteins) produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS (show NPS Proteins)/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions
the deletion of NPSR did not lead to compensatory changes in the vigilance-promoting effects of the CRF and Hcrt-1/Ox-A systems.
A single nucleotide polymorphism in Npsr1 that increases its activity is linked to higher anxiety.
In conclusion, the present study indicates that the NPS (show NPS Proteins)/NPSR system does not tonically control locomotion, sensitivity to diazepam, anxiety, depressive-like behaviours, memory and pain transmission in mice.
These results support an important role of neuropeptide S (show NPS Proteins) in regulating locomotor activity.
NPSR1 is essential in mediating NPS (show NPS Proteins) effects on behavior.
GPRA may contribute to the asthmatic phenotype by altering the activity of other pathways, such as neurally mediated mechanisms, that contribute to disease
The isolation and characterization of an arginine vasotocin receptor in mice is reported.
The interaction between 5-HTT (show SLC6A4 Proteins) (LL) and BDNF (A (show BDNF Proteins)+) increased the risk of anxiety, and the interaction between BDNF (A (show BDNF Proteins)+, GG) and NPSR1 (AA, T+) increased the risk of depression in asthmatic patients.
findings demonstrate that hNPS-(1-10) is a biased agonist favoring Galphaq (show GNAQ Proteins)-dependent signaling. It may represent a valuable chemical probe for further investigation of the therapeutic potential of human NPS (show NPS Proteins) receptor-directed signalingin vivo.
anxiety sensitivity correlated negatively with prefrontal activity in NPSR1 rs324981 carriers possibly suggesting a decompensation of the adaptive compensatory upregulation
Results suggest the functional NPSR1 gene A/T variant to influence glutamate (show GRIN1 Proteins)+glutamine (show GFPT1 Proteins) concentrations in the bilateral anterior cingulate cortex in healthy male subjects during CCK-4 (show PTK7 Proteins) induced panic
The T-allele of the NPSR1 rs324981 polymorphism is associated with increased impulsivity and ADHD-related traits in non-clinical cohorts.
The results suggest neuropeptide S receptor gene variation to be associated with alterations of prefrontal functioning in the attentional functions alerting and executive control partly modulated by anxiety sensitivity.
Results show that NPSR1 polymorphism is associated with AUD and alcohol consumption, dependent on sex, environment and age.
gene polymorphism is a risk factor for high IgE-associated atopic eczema at the age of two years in Finland if there is no probiotic treatment
The functional SNP rs324981 located in the gene of NPSR1 was significantly associated with objectively obtained sleep parameters in a sample of elderly white subjects
results suggest a potential protective function of the NPSR1 rs324981 A/A genotype against pathologically enhanced anxiety that might be explained by stronger reflective prefrontal regulation over the subcortical fear response.
GPRA variants are not an important contributor to childhood asthma and atopy susceptibility in a Mexican population.
This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.
G protein-coupled receptor 154
, G protein-coupled receptor PGR14
, G-protein coupled receptor 154
, G-protein coupled receptor PGR14
, neuropeptide S receptor
, vasotocin receptor
, G protein-coupled receptor for asthma susceptibility
, G-protein coupled receptor for asthma susceptibility
, vasopressin receptor-related receptor 1