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anti-Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) Antibodies

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Additionally we are shipping NPRL2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPRL2 56032 Q9WUE4
NPRL2 10641 Q8WTW4
NPRL2 363138  
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Top anti-NPRL2 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-TUSC4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: OVCAR-3 cell lysate Rabbit Anti-TUSC4 Antibody ,Paraffin Embedded Tissue: Human Adult Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TUSC4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB NPRL2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35µg/lane).This demonstrates the NPRL2 antibody detected the NPRL2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN238648 (0.1 ug/ml) staining of Human Muscle lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB NPRL2 Antibody (C-term)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NPRL2 antibody detected the NPRL2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details

NPRL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NPRL2 Antibodies

  1. Human Polyclonal NPRL2 Primary Antibody for EIA, WB - ABIN955400 : Spielewoy, Guaderrama, Wohlschlegel, Ashe, Yates, Wittenberg: Npr2, yeast homolog of the human tumor suppressor NPRL2, is a target of Grr1 required for adaptation to growth on diverse nitrogen sources. in Eukaryotic cell 2010 (PubMed)
    Show all 3 references for ABIN955400

  2. Cow (Bovine) Polyclonal NPRL2 Primary Antibody for IHC, WB - ABIN2773969 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)

  3. Human Polyclonal NPRL2 Primary Antibody for ELISA, WB - ABIN238648 : Ueda, Kawashima, Ohtani, Deng, Ravoori, Bankson, Gao, Girard, Minna, Roth, Kundra, Ji: The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells. in Cancer research 2006 (PubMed)

More Antibodies against NPRL2 Interaction Partners

Human Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) interaction partners

  1. NPRL2 mutations are significant cause of focal epilepsy.

  2. NPRL2 acts as a functional tumor suppressor in colorectal cancer cell lines.

  3. NPRL2 enhances sensitivity to oxaliplatin in colon cancer cells.

  4. Decreased expression of NPRL2 is associated with renal cancer.

  5. NPRL2 mRNA blood levels could be a potentially useful marker for the detection of early stage adenomas and colorectal cancers.

  6. Results provide a set of genetic and biologic proofs that TUSC4 functions as a bona fide tumor suppressor by regulating the protein stability and function of BRCA1 in breast cancer.

  7. NPRL2 expression is negatively related with the survival of osteosarcoma patients, indicating its value as a prognosis factor of osteosarcoma.

  8. Lower NPRL2 expression was observed significantly more frequently in poorly differentiated tumor samples than in highly or moderately differentiated colon tumors.

  9. tumor suppressor genes RBSP3/CTDSPL (show CTDSPL Antibodies), NPRL2/G21 and RASSF1A (show RASSF1 Antibodies) are downregulated in primary non-small cell lung cancer

  10. Data indicate that Npr2, a homolog of human NPRL2, is a phosphorylation-dependent target of the SCF (show KITLG Antibodies)(Grr1) E3 ubiquitin ligase (show MUL1 Antibodies) that plays a role in cell growth on some nitrogen sources.

NPRL2 Antigen Profile

Protein Summary

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.

Gene names and symbols associated with NPRL2

  • nitrogen permease regulator-like 2 (Nprl2) antibody
  • nitrogen permease regulator-like 2 (nprl2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (NPRL2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (Nprl2) antibody
  • nitrogen permease regulator-like 2 (S. cerevisiae) (nprl2) antibody
  • 2810446G01Rik antibody
  • G21 antibody
  • im:6900399 antibody
  • NPR2 antibody
  • npr2l antibody
  • TUSC4 antibody
  • zgc:153630 antibody

Protein level used designations for NPRL2

NPR2-like protein , gene 21 protein , nitrogen permase homolog , nitrogen permease regulator 2-like protein , tumor suppressor candidate 4 , 2810446G01Rik , G21 protein , homologous to yeast nitrogen permease (candidate tumor suppressor)

GENE ID SPECIES
56032 Mus musculus
379794 Xenopus laevis
10641 Homo sapiens
476614 Canis lupus familiaris
508487 Bos taurus
363138 Rattus norvegicus
559391 Danio rerio
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