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Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Additionally we are shipping and NCAPD3 Kits (1) and many more products for this protein.
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Human Polyclonal NCAPD3 Primary Antibody for IP, WB - ABIN151118
Wood, Liang, Li, Chen: Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair. in The Journal of biological chemistry 2008
Show all 2 Pubmed References
CAP-D3 down-regulates transcription of genes that encode amino acid transporters (SLC7A5 (show SLC7A5 Antibodies) and SLC3A2 (show SLC3A2 Antibodies)) to promote bacterial autophagy by colon epithelial cells.
The initial phase of chromosome condensation requires Cdk1 (show CDK1 Antibodies)-mediated phosphorylation of the CAP-D3 subunit of condensin II.
hCAP-D3 is a new biomarker for subtype-1 prostate tumors that improves prognostication.
We show here that protein phosphatase 2A (PP2A (show PPP2R4 Antibodies)), which interacts with condensin II but not condensin I, plays an essential role in targeting condensin II to chromosomes.
The CAP-D3 subunit of the condensin II complex implicated in chromosome assembly and segeregation
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003
non-SMC condensin II complex, subunit D3
, condensin II non-SMC subunit
, condensin-2 complex subunit D3
, condensin-2 complex subunit D3-like
, Jacobsen syndrome region 2