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NUCB2 encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. Additionally we are shipping Nucleobindin 2 Antibodies (136) and Nucleobindin 2 Proteins (39) and many more products for this protein.
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Human NUCB2 ELISA Kit for Sandwich ELISA - ABIN1706085
Oh-I, Shimizu, Satoh, Okada, Adachi, Inoue, Eguchi, Yamamoto, Imaki, Hashimoto, Tsuchiya, Monden, Horiguchi, Yamada, Mori: Identification of nesfatin-1 as a satiety molecule in the hypothalamus. in Nature 2006
Show all 2 references for ABIN1706085
Rat (Rattus) NUCB2 ELISA Kit - ABIN572349
Aydin: Role of NUCB2/nesfatin-1 as a possible biomarker. in Current pharmaceutical design 2013
Show all 2 references for ABIN572349
It is confirmed herein that nesfatin-1 can regulate appetite in the pig and affect the gonadotropic axis of the prepubertal pig
Suggest that catecholaminergic and c-fos immunoreactive NUCB2/nesfatin-1 neurons could contribute in the anorexigenic effects of the mycotoxin deoxynivalenol.
nesfatin-1 might have an important role in regulation of food intake and pathogenesis of loss of appetite in children.
Nesfatin-1 levels were significantly lower in metabolic syndrome (MS) group compared to non-MS group
These results corroborate the suggestion of NUCB2/nesfatin-1 being relevantly involved in the regulation of mood and stress in a sex-specific way
Serum nesfatin-1 levels are significantly higher in girls with premature thelarche compared to prepubertal controls.
Circulating NUCB2/nesfatin-1 levels correlated positively with perceived anxiety, whereas no association with body mass index or eating disorder symptoms was observed.
Our results show that NUCB2 plays an important role in tumorigenesis and progression and is a potential molecular biomarker for the diagnosis and targeted therapy of ccRCC.
This investigation indicates a marked association of serum and synovial fluid nesfatin-1 concentrations with osteoarthritis disease severity.
This study shows an association of serum nesfatin-1 concentrations and the development and severity of peripheral arterial disease in type 2 diabetes mellitus patients.
Plasma IL-6 (show IL6 ELISA Kits) and TNF-alpha (show TNF ELISA Kits) did not significantly change after training, but nesfatin increased significantly only with high-intensity interval training compared with the control group.
nesfatin-1 inhibits the growth of adrenocortical H295R cells and promotes apoptosis, potentially via the involvement of Bax (show BAX ELISA Kits), BCL-XL (show BCL2L1 ELISA Kits) and BCL-2 (show BCL2 ELISA Kits) genes as well as ERK1/2 (show MAPK1/3 ELISA Kits), p38 (show CRK ELISA Kits) and JNK1 (show MAPK8 ELISA Kits)/2 signalling cascades
Polymorphism in the exon 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 and 11 of bovine NUCB2 gene was detected in 686 individuals from three Chinese cattle breeds.
reproductive-endocrine regulation through hypothalamus-pituitary-ovary axis may contribute to nesfatin-1/NUCB2 expression in the pituitary gland.
new information on the cell specific localization of NUCB2/nesfatin-1 in the intestinal mucosa, and a novel function for nesfatin-1 in modulating intestinal CCK (show CCK ELISA Kits) and PYY expression and secretion
MGN3-1 cells respond differently to nutrients in secreting NUCB2/nesfatin-1 and ghrelin (show GHRL ELISA Kits). Similarly, acute or chronic intake of nutrients does influence NUCB2 mRNA expression and NUCB2/nesfatin-1 release in a diet specific manner.
Our data suggested that nesfatin-1 exerted its neuroprotective effect on dopaminergic cells against rotenone by ameliorating mitochondrial dysfunction and its anti-apoptotic property.
NUCB2/nesfatin-1 is co-localized with GLP-1 (show GCG ELISA Kits) and GIP (show GIP ELISA Kits) in small intestinal cells. Data support the hypothesis that nesfatin-1 is present in enteroendocrine cells and that it stimulates incretin secretion.
These results indicate that paraventricular nucleus NUCB2/nesfatin-1 is directly targeted by leptin (show LEP ELISA Kits), and mediates its anorexigenic effect.
influence of nesfatin-1 on lipid metabolism either in physiological or diabetic conditions
study demonstrated cytoplasmic localization of NUCB2/nesfatin-1 peptide in both human and murine chondrocytes.
pro-osteogenic activity of NUCB2(1-83)
These data indicate that secreted Nucleobindin-2 is a suppressor of adipocyte differentiation through inhibition of cAMP production and insulin (show INS ELISA Kits) signal.
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains.
, DNA-binding protein NEFA
, gastric cancer antigen Zg4
, nucleobinding 2