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anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Antibodies

NOD2 is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). Additionally we are shipping NOD2 Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NOD2 64127 Q9HC29
NOD2 257632  
NOD2 291912  
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Top anti-NOD2 Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of NOD2 in HeLa cells with this product at 10 μg/ml. Western blot analysis of NOD2 in HeLa cell lysate with this product at (A) 2 and (B) 4 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185703 (0.1µg/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunocytochemistry of NOD2 in Jurkat cells with this product at 5 μg/ml. Western blot analysis of NOD2 in Jurkat cell lysate with this product at (A) 1, (B) 2 and (C) 4 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, WB 50 μg Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), IP, WB 100 μL Log in to see 5 to 6 Days
$506.80
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$244.59
Details
Mouse Rat Un-conjugated WB Immunoblot of 293T cell control lysate (1) and 293T cells transfected with mouse NOD2 (2). 2 x105 cells were loaded per lane, resolved by SDS-PAGE and transferred to PVDF. The blots were then probed with 2 µg/ml of 26mNOD2 antibody followed by polyclonal anti-rat secondary antibody conjugated to HRP and visualized by chemiluminescence. 100 μg Log in to see 5 to 6 Days
$276.57
Details

NOD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NOD2 Antibodies

  1. Human Polyclonal NOD2 Primary Antibody for EIA, IHC (p) - ABIN500363 : Inohara, Koseki, del Peso, Hu, Yee, Chen, Carrio, Merino, Liu, Ni, Núñez: Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN500363

  2. Human Polyclonal NOD2 Primary Antibody for EIA, IF - ABIN500365 : Ogura, Inohara, Benito, Chen, Yamaoka, Nunez: Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN500365

  3. Human Monoclonal NOD2 Primary Antibody for BCA - ABIN2666357 : Miceli-Richard, Lesage, Rybojad, Prieur, Manouvrier-Hanu, Häfner, Chamaillard, Zouali, Thomas, Hugot: CARD15 mutations in Blau syndrome. in Nature genetics 2001 (PubMed)
    Show all 3 references for ABIN2666357

  4. Human Polyclonal NOD2 Primary Antibody for IF, WB - ABIN318706 : Inohara, Nuñez: NODs: intracellular proteins involved in inflammation and apoptosis. in Nature reviews. Immunology 2003 (PubMed)
    Show all 3 references for ABIN318706

  5. Mouse (Murine) Monoclonal NOD2 Primary Antibody for WB - ABIN280900 : Zanello, Goethel, Forster, Geddes, Philpott, Croitoru: Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis. in PLoS ONE 2013 (PubMed)

  6. Human Polyclonal NOD2 Primary Antibody for ELISA, WB - ABIN185703 : Keshav: Paneth cells: leukocyte-like mediators of innate immunity in the intestine. in Journal of leukocyte biology 2006 (PubMed)

  7. Human Monoclonal NOD2 Primary Antibody for ICC, IF - ABIN1721812 : Cooney, Baker, Brain, Danis, Pichulik, Allan, Ferguson, Campbell, Jewell, Simmons: NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. in Nature medicine 2010 (PubMed)

More Antibodies against NOD2 Interaction Partners

Human Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Significant associations were found between Crohn's disease (CD) and minor NOD2 variants, as well as TLR4 (show TLR4 Antibodies) 299Gly, TNF-alpha (show TNF Antibodies) G-308A, IL-6 (show IL6 Antibodies) G-174C and IL-1RN (show IL1RN Antibodies) VNTR A2 variants, while ulcerative colitis (UC) was associated only with IL-1RN (show IL1RN Antibodies) VNTR A2 variants.

  2. CaSR (show CASR Antibodies)-induced constitutive macropinocytosis facilitates the sentinel function of macrophages, promoting the efficient delivery of ligands to cytosolic pattern-recognition receptors.

  3. The INCA (show CARD17 Antibodies) trial (impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver cirrhosis and ascites): precision medicine for patients with liver cirrhosis and ascites

  4. This is the first description of gonosomal NOD2 mosaicism as the cause of intrafamilial recurrence of Blau syndrome.

  5. the rs2066847 variant of the NOD2/CARD15 gene is not associated with lung cancer risk in the Turkish population

  6. data describe donor NOD2 SNP13 as a significant risk factor for the development of septic shock after allogeneic stem cell transplantation

  7. NOD1 (show NOD1 Antibodies) and NOD2, two members of the NOD-like receptor family of pattern recognition receptors, are important mediators of ER-stress-induced inflammation in mouse and human cells

  8. Blau syndrome has been strongly associated with mutations in the NOD2 gene. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201507-1344LE#.VrgfNNL2byA

  9. None of the NOD2/CARD15 variants was statistically associated to CRC (show CALR Antibodies) susceptibility in our Malaysian population.

  10. data demonstrate that in Crohn's disease patients the IVS4+10 A>C NOD2 variant is strongly associated with the development of perianal fistulas

Mouse (Murine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. CD44 (show CD44 Antibodies), NOD2, and Fas (show FAS Antibodies) have distinct functions in regulating changes in trabecular and cortical bone indices during unloading.

  2. The results indicate that Nod1 (show NOD1 Antibodies) cooperates with Nod2 or TLRs to produce cytokines in macrophages in response to M. tuberculosis infection.

  3. Myocardial ischemia reperfusion injury markedly up-regulated NOD2 expression in heart tissue.

  4. A novel crosstalk between TLR4 (show TLR4 Antibodies)- and NOD2-mediated signaling in the regulation of intestinal inflammation

  5. Nod2-/- alveolar macrophages and blood neutrophils displayed a reduced capacity to internalize pneumococci in vitro.

  6. NOD1 (show NOD1 Antibodies) and NOD2, play a collaborative role in T cell activation by alloantigen and that their blockade in vitro can inhibit T cell responses.

  7. NOD2 and its downstream adaptor protein IPS-1 (show ISYNA1 Antibodies) have been found to be essential for LTB4 (show PTGR1 Antibodies)-mediated effects against IAV infection.

  8. helminth infection protects mice deficient in the Crohn's disease susceptibility gene Nod2 from intestinal abnormalities by inhibiting colonization by an inflammatory Bacteroides species.

  9. NOD1 (show NOD1 Antibodies) and NOD2, two members of the NOD-like receptor family of pattern recognition receptors, are important mediators of ER-stress-induced inflammation in mouse and human cells

  10. Macrophages from nod2 mutant R314Q mice and from patients from Blau syndrome showed reduced cytokine production and intracellular signaling of pathways normally activated by muramyl dipeptide

Cow (Bovine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.

  2. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.

  3. Genetic variation and putative regulatory regions in bovine CARD15.

  4. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.

NOD2 Antigen Profile

Protein Summary

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Gene names and symbols associated with NOD2

  • caspase recruitment domain 15 protein (TTHERM_01951320) antibody
  • nucleotide-binding oligomerization domain containing 2 (NOD2) antibody
  • nucleotide-binding oligomerization domain containing 2 (Nod2) antibody
  • ACUG antibody
  • BLAU antibody
  • Card15 antibody
  • CD antibody
  • CLR16.3 antibody
  • F830032C23Rik antibody
  • IBD1 antibody
  • Nlrc2 antibody
  • NOD2B antibody
  • PSORAS1 antibody

Protein level used designations for NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2

GENE ID SPECIES
7828465 Tetrahymena thermophila
64127 Homo sapiens
257632 Mus musculus
291912 Rattus norvegicus
444867 Bos taurus
454083 Pan troglodytes
Selected quality suppliers for anti-NOD2 (NOD2) Antibodies
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