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NACC1 encodes a member of the BTB/POZ protein family. Additionally we are shipping Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Proteins (3) and many more products for this protein.
Showing 10 out of 90 products:
Human Monoclonal NACC1 Primary Antibody for ICC, FACS - ABIN259549
Nakayama, Nakayama, Davidson, Sheu, Jinawath, Santillan, Salani, Bristow, Morin, Kurman, Wang, Shih: A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 10 references for ABIN259549
Human Monoclonal NACC1 Primary Antibody for EIA, IHC (p) - ABIN1108376
Korutla, Wang, Lewis, Neustadter, Stromberg, Mackler: Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1. in Neuroscience 2002
Show all 2 references for ABIN1108376
Human Monoclonal NACC1 Primary Antibody for IHC, ELISA - ABIN969307
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
Human Polyclonal NACC1 Primary Antibody for ELISA, WB - ABIN188846
Wang, Rao, Chu, Shen, Levasseur, Theunissen, Orkin: A protein interaction network for pluripotency of embryonic stem cells. in Nature 2006
Cow (Bovine) Polyclonal NACC1 Primary Antibody for WB - ABIN2775934
Yeasmin, Nakayama, Ishibashi, Katagiri, Iida, Purwana, Nakayama, Miyazaki: Expression of the bric-a-brac tramtrack broad complex protein NAC-1 in cervical carcinomas seems to correlate with poorer prognosis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Cow (Bovine) Polyclonal NACC1 Primary Antibody for IHC, WB - ABIN2775909
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
SCN1A (show SCN1A Antibodies) mutations may alter axonal function, causing motor neuropathy/neuronopathy. This may contribute to gait disturbance and orthopedic misalignment, which is characteristic of patients with Dravet syndrome.
The association study indicated that age at first seizure and frameshift mutations of SCN1A (show SCN1A Antibodies) were associated with Dravet syndrome.
NAC1 forms a protein complex to function as a transcriptional regulator in cancer cells
a mutation in NACC1 causes microcephaly, profound developmental delays and/or intellectual disability, cataracts, severe epilepsy including infantile spasms, irritability, failure to thrive, and stereotypic hand movements
Study reported the range of rare copy number variants found in SCN1A (show SCN1A Antibodies) gene in a series of Welsh patients with childhood-onset epilepsy and intellectual disability and identified clearly or likely pathogenic CNVs in 8.8 % of the patients including 5 rare de novo deletions.
Our findings suggest that SCN1A (show SCN1A Antibodies) mutation leads to changes in the dopamine system that may contribute to the behavioral abnormalities in DS.
This study demonstrated that a significant higher frequency of the AG genotype (p=0.001) and G allele (p=0.006) of SCN1A (show SCN1A Antibodies) polymorphism in epileptic patients than in controls.
miR (show MLXIP Antibodies)-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 and BCL6 (show BCL6 Antibodies). miR (show MLXIP Antibodies)-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 had a predictive value for ovarian cancer progression
Dravet syndrome is associated with mutations in the sodium channel alpha1 subunit gene (SCN1A (show SCN1A Antibodies)) in 70-80% of individuals.
The presence of SCN1A (show SCN1A Antibodies) mutations and absence of mutations in ATP1A2 (show ATP1A2 Antibodies) or CACNA1A (show CACNA1A Antibodies) suggest that the Polish patients represent FHM (show CACNA1A Antibodies) type 3.
a sub-network of four factors, Nac1, Oct4 (show POU5F1 Antibodies), Tcf3 (show TCF7L1 Antibodies), and Sox2 (show SOX2 Antibodies), regulates mouse embryonic stem cell differentiation into the alternative mesendodermal and neuroectodermal fates.
The interaction of Nac1 with Miz1 (show PIAS2 Antibodies) may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.
NAC1 participates in the motility and differentiation of developing chondrocytes and cartilaginous tissues, and its expression is necessary to maintain normal axial patterning of murine skeleton.
The mouse Nac1 gene consist of six exons, with exon 2 containing an alternative splice donor, providing a molecular explanation of the splice variants observed in mouse and rat.
these data indicate involvement of NAC1 in the acute behavioral and neurochemical responses to psychomotor stimulants
Nanog (show NANOG Antibodies) interacts with Nac1 through WNAAP to regulate the cell cycle of stem cells via the ERas/phosphatidylinositol 3-kinase/Akt (show AKT1 Antibodies) pathway, but not pluripotency
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.
BEN domain containing 8
, BTB/POZ domain-containing protein 14B
, nucleus accumbens-associated protein 1
, transcriptional repressor NAC1
, nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
, BTB (POZ) domain containing 14B
, nucleus accumbens-1
, sodium channel protein type 1 subunit alpha
, sodium channel protein type I subunit alpha
, sodium channel protein, brain I alpha subunit
, sodium channel voltage gated type 1 alpha subunit
, sodium channel, voltage-gated, type I, alpha polypeptide
, voltage-gated sodium channel subunit alpha Nav1.1