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anti-Oligophrenin 1 (OPHN1) Antibodies

OPHN1 encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Additionally we are shipping Oligophrenin 1 Proteins (5) and Oligophrenin 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OPHN1 4983 O60890
OPHN1 94190 Q99J31
OPHN1 312108 P0CAX5
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Top anti-Oligophrenin 1 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged OPHN1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged OPHN1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.08 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.45 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated   50 μL Log in to see 9 to 14 Days
$417.00
Details
Human Mouse Un-conjugated ELISA (Capture), ELISA, WB   100 μg Log in to see 6 to 8 Days
$487.30
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 9 to 14 Days
$574.35
Details

OPHN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Oligophrenin 1 Antibodies

  1. Human Monoclonal Oligophrenin 1 Primary Antibody for ELISA, WB - ABIN395392 : Piton, Gauthier, Hamdan, Lafrenière, Yang, Henrion, Laurent, Noreau, Thibodeau, Karemera, Spiegelman, Kuku, Duguay, Destroismaisons, Jolivet, C�té, Lachapelle, Diallo, Raymond, Marineau, Champagne, Xiong, Gaspar, Rivière, Tarabeux, Cossette, Krebs, Rapopo: Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia. in Molecular psychiatry 2011 (PubMed)
    Show all 5 references for ABIN395392

More Antibodies against Oligophrenin 1 Interaction Partners

Human Oligophrenin 1 (OPHN1) interaction partners

  1. A neuronal stem cell-based model for the treatment of OPHN1 syndrome and other neurological disorders due to ROCK dysfunction.

  2. results suggest that oligophrenin-1 is involved in tumor progression in prostate cancer

  3. This is the first description of an in-frame deletion within the BAR domain of OPHN1 and could provide new insights into the role of this domain in relation to brain and cognitive development or function.

  4. Our results demonstrate that multiple post-transcriptional events occur on OPHN1, a gene playing an important role in brain function and development.

  5. In response to GPVI (show GP6 Antibodies) stimulation, OPHN1 becomes phosphorylated at Tyr370 and plays a role in the formation of filopodia during platelet spreading on collagen.

  6. Several genes expressed at exceptionally high levels were identified associated with early oocyte development, TMEFF2 (show TMEFF2 Antibodies), the Rho-GTPase-activating protein (show STARD13 Antibodies) oligophrenin 1 (OPHN1) and the mitochondrial-encoded ATPase6 (ATP6 (show MT-ATP6 Antibodies)).

  7. This mutation determines the production of a mutant oligophrenin 1 protein with 16 extra amino acids inserted in-frame in the N-terminal BAR (Bin1 (show BIN1 Antibodies)/amphiphysin (show AMPH Antibodies)/Rvs167) domain. (oligophrenin 1 protein )

  8. Data suggest that OPHN1 defect may be an important contributory factor to XLMR (show DLG3 Antibodies).

  9. The OPHN1 gene plays a role during the development of the human cerebellum.

  10. Oligophrenin 1 mutations were found in 12% (2/17) of individuals with mental retardatin and known cerebellar anomalies and in 1% (2/196) of the X-linked mental retardation group.

Mouse (Murine) Oligophrenin 1 (OPHN1) interaction partners

  1. Identify OPHN1 as an important regulator of platelet cytoskeletal reorganization and thrombus formation.

  2. OPHN1 is a bifunctional protein that is able, through distinct mechanisms, to regulate and most likely link exocytosis to compensatory endocytosis in chromaffin cells.

  3. OPHN1 is a powerful regulator of Rho GTPase (show RACGAP1 Antibodies) activity in platelets that is critical for the reorganization of the cytoskeleton, which is a major process required for stable platelet adhesion and thrombus formation to occur.

  4. Ophn1 is involved in processes of normal retinal vessel function during adulthood.

  5. our data establish a role for rapid OPHN1 synthesis in mGluR (show GRM8 Antibodies) long-term depression.

  6. The results of this study indicated the presence of a circadian oscillator in the hippocampus, involving the clock gene Bmal1 (show ARNTL Antibodies) (also known as Arntl (show ARNTL Antibodies)), that is modulated by Rev-erbalpha (show NR1D1 Antibodies) and requires oligophrenin-1 for normal oscillation.

  7. Oligophrenin-1 is expressed in developing CNS areas that evince synaptic plasticity. OPHN1 is expressed in both glial and neuronal cells, where it colocalizes with actin at the tip of growing neurites.

  8. This study indicates that cognitive impairment related to OPHN1 loss of function is associated with both presynaptic and postsynaptic alterations.

  9. Loss of OPHN1 leads to the activation of the RhoA (show RHOA Antibodies)/ROCK signaling pathway.

  10. Results sugest that reduced or defective OPHN1 signaling impairs synaptic vesicle cycling at hippocampal synapses.

Cow (Bovine) Oligophrenin 1 (OPHN1) interaction partners

  1. OPHN1 is a bifunctional protein that is able, through distinct mechanisms, to regulate and most likely link exocytosis to compensatory endocytosis in chromaffin cells.

Oligophrenin 1 (OPHN1) Antigen Profile

Protein Summary

This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.

Gene names and symbols associated with anti-Oligophrenin 1 (OPHN1) Antibodies

  • oligophrenin-1-like (LOC100065450) antibody
  • oligophrenin 1 (ophn1) antibody
  • oligophrenin 1 (OPHN1) antibody
  • oligophrenin 1 (Tsp_13482) antibody
  • oligophrenin 1 (Ophn1) antibody
  • oligophrenin-1-like (LOC525644) antibody
  • ARHGAP41 antibody
  • C130037N19Rik antibody
  • MGC68856 antibody
  • MRX60 antibody
  • OPHN1 antibody
  • Opn1 antibody
  • zgc:92603 antibody

Protein level used designations for anti-Oligophrenin 1 (OPHN1) Antibodies

oligophrenin 1 , oligophrenin-1 , mental retardation, X-linked 60 , oligophrenin-1, Rho-GTPase activating protein

GENE ID SPECIES
100065450 Equus caballus
379682 Xenopus laevis
422162 Gallus gallus
436982 Danio rerio
703141 Macaca mulatta
710787 Macaca mulatta
779935 Xenopus (Silurana) tropicalis
10901254 Trichinella spiralis
100379222 Cavia porcellus
100554128 Anolis carolinensis
4983 Homo sapiens
94190 Mus musculus
312108 Rattus norvegicus
607363 Canis lupus familiaris
449628 Pan troglodytes
525644 Bos taurus
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