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Origin Recognition Complex, Subunit 4 Proteins (ORC4)

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Additionally we are shipping ORC4 Antibodies (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ORC4 ORC4 252936  
ORC4 5000 O43929
ORC4 26428 O88708
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Top ORC4 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ORC4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Origin Recognition Complex, Subunit 4 (ORC4) Interaction Partners

Fruit Fly (Drosophila melanogaster) Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

  1. Spotted-dick is a zinc-finger protein of Drosophila required for expression of Orc4 and S phase

Human Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

  1. compared with homozygous missense mutations, compound heterozygous mutations appeared to have a more severe effect on phenotype, causing more severe growth retardation in ORC4

  2. identified three different mutations in the gene encoding ORC4, a component of the eukaryotic origin recognition complex, in five individuals with Meier-Gorlin syndrome

  3. Study using HCT116 haplo-insufficient (show TGFb Proteins) cells and Orc2 hypomorphic cells demonstrates that the binding of human Ku to replication origins precedes that of Orc-3 (show ORC3 Proteins), -4, and -6 subunit binding.

  4. describe 3 patients with B-cell lymphoproliferative disorders (2 with non-Hodgkin lymphoma and 1 with nonsecretory multiple myeloma) carrying a novel A286V mutation within ORC4L gene

Mouse (Murine) Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

  1. ORC4 surrounds the chromatin that will be extruded in the polar body in both female meiotic divisions, then makes a transition from the cytoplasm to the chromosomes at zygotic anaphase, suggesting multiple roles for this replication licensing protein.

ORC4 Protein Profile

Protein Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Gene names and symbols associated with ORC4

  • Origin recognition complex subunit 4 (Orc4)
  • origin recognition complex, subunit 4-like 2 (Orc4l2)
  • origin recognition complex, subunit 4 (orc4)
  • origin recognition complex subunit 4 (orc4)
  • origin recognition complex subunit 4 (ORC4)
  • origin recognition complex subunit 4 (CNM01830)
  • origin recognition complex subunit 4 (LOC100285482)
  • origin recognition complex, subunit 4 (ORC4)
  • origin recognition complex, subunit 4 (Orc4)
  • ATORC4 protein
  • CG2917 protein
  • Dmel\\CG2917 protein
  • dmOrc4 protein
  • F23H14.9 protein
  • F23H14_9 protein
  • fc50c03 protein
  • mMmORC4 protein
  • ORC protein
  • Orc4 protein
  • orc4l protein
  • Orc4P protein
  • origin recognition complex subunit 4 protein
  • rDmORC protein
  • wu:fc50c03 protein
  • zgc:85772 protein

Protein level used designations for ORC4

CG2917-PA , CG2917-PB , Orc4-PA , Orc4-PB , origin recognition complex subunit 4 , origin recognition complex, subunit 4 , origin recognition complex, subunit 4 homolog , origin recognition complex, subunit 4-like

GENE ID SPECIES
37970 Drosophila melanogaster
252936 Rattus norvegicus
406462 Danio rerio
541939 Zea mays
814641 Arabidopsis thaliana
3255276 Cryptococcus neoformans var. neoformans JEC21
100285482 Zea mays
5000 Homo sapiens
26428 Mus musculus
476141 Canis lupus familiaris
529245 Bos taurus
295596 Rattus norvegicus
397923 Xenopus laevis
424307 Gallus gallus
100689043 Cricetulus griseus
Selected quality suppliers for ORC4 Proteins (ORC4)
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