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Ornithine Aminotransferase Proteins (OAT)

OAT encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Additionally we are shipping OAT Kits (8) and OAT Antibodies (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse OAT OAT 18242 P29758
OAT 64313 P04182
OAT 4942 P04181
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Top OAT Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Rat His tag 1 mg Log in to see 56 to 66 Days
$3,120.33
Details
Yeast Plasmodium falciparum His tag 1 mg Log in to see 56 to 66 Days
$3,151.50
Details
Yeast Cow His tag 1 mg Log in to see 56 to 66 Days
$3,151.50
Details
Yeast REACT_Moth bean His tag 1 mg Log in to see 56 to 66 Days
$3,188.17
Details
Yeast Emericella nidulans His tag 1 mg Log in to see 56 to 66 Days
$3,274.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 1 mg Log in to see 3 to 4 Days
$2,524.50
Details
Human Un-conjugated 5 μg Log in to see 6 Days
$168.54
Details

OAT Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human

More Proteins for Ornithine Aminotransferase (OAT) Interaction Partners

Mouse (Murine) Ornithine Aminotransferase (OAT) interaction partners

  1. The data highlight the importance of OAT in ornithine metabolism, especially in the liver, and suggest a post-transcriptional regulation of OAT by LPS (show TLR4 Proteins) in the liver.

  2. in female and castrated male mice devoided of testosterone, OAT gene is highly expressed and L-ornithine is converted into L-glutamate (show GRIN1 Proteins).

  3. In H4Flox liver, glutamine synthetase (GS (show GLUL Proteins)), ornithine aminotransferase (OAT) and thyroid hormone-receptor (show THRA Proteins) beta1 (TRbeta1 (show THRB Proteins)) were exclusively expressed in pericentral hepatocytes.

  4. Sexual dimorphism of Oat expression in the kidney was observed.

Human Ornithine Aminotransferase (OAT) interaction partners

  1. Sequencing of the gene for ornithine aminotransferase reveals a homozygous mutation in our patient (base exchange c.498C>A in Exon 4).

  2. Neurogenesis is inhibited by X-OAT during Xenopus embryonic development, but it is essential for Xenopus embryonic development. The Arg 180 and Leu 402 are crucial for these effects of the OAT molecule in development.

  3. Our report describes the first case of gyrate atrophy in the Korean population diagnosed by OAT gene analysis and treated with vitamin B6 dietary supplementation.

  4. We identified a novel frameshift mutation (p.K169DfsX10) in the OAT gene. While an early arginine-restricted dietary treatment suppressed the fundus changes

  5. Data suggest that other factors besides the specific ornithine aminotransferase (OAT) genotype modulate atrophy of choroid and retina (GA) phenotype in patients.

  6. OAT was a highly homologous and stable protein located in the mitochondria.

  7. Molecular analysis revealed a new deletion c.532_536delTGGGG (p.Trp178X) and a known mutation c.897C>G (p.Tyr299X) in the OAT gene.

  8. Fundus autofluorescence imaging can reveal the extent of neurosensory dysfunction in gyrate atrophy patients.

  9. analysis of ornithine aminotransferase substrate specificity

OAT Protein Profile

Protein Summary

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

Gene names and symbols associated with OAT

  • Ornithine aminotransferase precursor (Oat)
  • ornithine aminotransferase (oat)
  • ornithine aminotransferase (OAT)
  • ornithine aminotransferase (Lbys_2951)
  • ornithine aminotransferase (Riean_0998)
  • ornithine aminotransferase (Ftrac_2019)
  • ornithine aminotransferase (Celal_2605)
  • ornithine aminotransferase (Deipr_1149)
  • ornithine aminotransferase (Celly_0230)
  • ornithine aminotransferase (Weevi_2065)
  • ornithine aminotransferase (Fluta_4071)
  • ornithine aminotransferase (Halhy_2848)
  • ornithine aminotransferase (Theth_0565)
  • ornithine aminotransferase (Oat)
  • 151832_at protein
  • AI194874 protein
  • CG8782 protein
  • Dmel\\CG8782 protein
  • GACR protein
  • HOGA protein
  • OATASE protein
  • OKT protein
  • rOAT protein

Protein level used designations for OAT

CG8782-PA , Oat-PA , ornithine aminotransferase , ornithine aminotransferase precursor , ornithine aminotransferase (gyrate atrophy) , ornithine aminotransferase, mitochondrial , ornithine--oxo-acid aminotransferase , gyrate atrophy , ornithine delta-aminotransferase , ornithine-oxo-acid aminotransferase

GENE ID SPECIES
40145 Drosophila melanogaster
379754 Xenopus laevis
450803 Pan troglodytes
477858 Canis lupus familiaris
9956831 Leadbetterella byssophila DSM 17132
10001754 Riemerella anatipestifer ATCC 11845 = DSM 15868
10012165 Marivirga tractuosa DSM 4126
10145026 Cellulophaga algicola DSM 14237
10256630 Deinococcus proteolyticus MRP
10262214 Cellulophaga lytica DSM 7489
10283330 Weeksella virosa DSM 16922
10399445 Fluviicola taffensis DSM 16823
10587022 Haliscomenobacter hydrossis DSM 1100
10885318 Thermotoga thermarum DSM 5069
100337582 Xenopus laevis
18242 Mus musculus
64313 Rattus norvegicus
4942 Homo sapiens
505323 Bos taurus
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