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Oxysterol Binding Protein-Like 1A Proteins (OSBPL1A)

OSBPL1A encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 1A Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OSBPL1A 114876 Q9BXW6
OSBPL1A 64291 Q91XL9
Rat OSBPL1A OSBPL1A 259221 Q8K4M9
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Top Oxysterol Binding Protein-Like 1A Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OSBPL1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Oxysterol Binding Protein-Like 1A (OSBPL1A) Interaction Partners

Human Oxysterol Binding Protein-Like 1A (OSBPL1A) interaction partners

  1. The L66P mutation in the first doublecortin domain of the Rp1 gene impairs Rp1 protein localization and function, leading to abnormalities in photoreceptor outer segment structure and progressive photoreceptor degeneration.

  2. We suggest that arRP patients with high myopic refractive error should be preferentially analysed for RP1 mutations.

  3. it reports that different regions of RP1 can also lead to arRCD.

  4. Two novel heterozygous null mutations in RP1 co-segregate with the disease in autosomal recessive retinitis pigmentosa patients.

  5. RP1 (show STK19 Proteins) phosphorylation at Ser (show SIGLEC1 Proteins)(236) by CK2 (show CSNK2A1 Proteins) seems to play a significant role in cell adhesion and might initiate new insights in the CK2 (show CSNK2A1 Proteins) and EB1 (show MAPRE2 Proteins) family protein association.

  6. Data found pathogenic DNA variants in the genes RP1 (show STK19 Proteins), USH2A, CNGB3 (show CNGB3 Proteins), NMNAT1 (show NMNAT1 Proteins), CHM (show CHM Proteins), and ABCA4 (show ABCA4 Proteins), responsible for retinitis pigmentosa, Usher syndrome, achromatopsia, Leber congenital amaurosis, choroideremia (show CHM Proteins), or recessive Stargardt/cone-rod dystrophy cases.

  7. The most severe missense mutation occurred in patients with p.D984G in RP1.

  8. A novel homozygous retinitis pigmentosa nonsense mutation in exon 4 of the RP1 gene, c.1012C>T (p.R338*) was identified in the proband and her two affected sisters.

  9. molecular mechanism of RP1 mutation

  10. ORP1S is a cytoplasmic sterol sensor, which transports sterols to the nucleus and promotes LXR (show NR1H3 Proteins) regulated trans-activation of apoE (show APOE Proteins).

Mouse (Murine) Oxysterol Binding Protein-Like 1A (OSBPL1A) interaction partners

  1. Osbpl1a silencing in macrophage foam cells enhances endosome motility and results in inhibition of [(3)H]cholesterol efflux to apolipoprotein A-I (show APOA1 Proteins).

  2. OSBP (show OSBP Proteins) regulates hepatic TG metabolism and suggest the involvement of OSBP (show OSBP Proteins) in the insulin (show INS Proteins) signaling pathways that control hepatic lipogenesis.

Oxysterol Binding Protein-Like 1A (OSBPL1A) Protein Profile

Protein Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist\; they encode different isoforms.

Gene names and symbols associated with OSBPL1A

  • oxysterol binding protein-like 1A (osbpl1a)
  • oxysterol-binding protein-related protein 1 (Tsp_09273)
  • oxysterol-binding protein-related protein 1 (Tsp_03387)
  • oxysterol binding protein-like 1A (OSBPL1A)
  • oxysterol binding protein-like 1A (Osbpl1a)
  • retinitis pigmentosa 1 (autosomal dominant) (RP1)
  • DCDC4A protein
  • DKFZp459N1538 protein
  • G430090F17Rik protein
  • Gm753 protein
  • ORP-1 protein
  • ORP1 protein
  • Osbpl1b protein
  • si:dkey-121a11.8 protein

Protein level used designations for OSBPL1A

oxysterol-binding protein-related protein 1 , oxysterol-binding protein-like 1A , oxysterol binding protein-like 1A , oxysterol binding protein-like protein 1A , oxysterol-binding protein-related protein 1-like , OSBP-related protein 1 , oxysterol binding protein-like 1B , oxysterol-binding protein-related protein 1 variant 1 , oxysterol-binding protein-related protein 1 variant 2 , ORP-1 , oxygen-regulated protein 1 , retinitis pigmentosa 1 protein , retinitis pigmentosa RP1 protein

GENE ID SPECIES
565503 Danio rerio
10905070 Trichinella spiralis
10909128 Trichinella spiralis
100174299 Pongo abelii
421079 Gallus gallus
468500 Pan troglodytes
495678 Xenopus laevis
677867 Macaca mulatta
100010444 Monodelphis domestica
100127588 Xenopus (Silurana) tropicalis
100356707 Oryctolagus cuniculus
100403124 Callithrix jacchus
100480218 Ailuropoda melanoleuca
100511459 Sus scrofa
100540838 Meleagris gallopavo
100557357 Anolis carolinensis
100600026 Nomascus leucogenys
114876 Homo sapiens
480761 Canis lupus familiaris
616555 Bos taurus
64291 Mus musculus
259221 Rattus norvegicus
6101 Homo sapiens
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