Oxysterol Binding Protein-Like 1A Proteins (OSBPL1A)

OSBPL1A encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 1A Antibodies (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OSBPL1A 114876 Q9BXW6
OSBPL1A 64291 Q91XL9
Rat OSBPL1A OSBPL1A 259221 Q8K4M9
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Top Oxysterol Binding Protein-Like 1A Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process IDH1 dissolution curves 1 mg Log in to see 70 Days
$12,127.90
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$554.07
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OSBPL1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Oxysterol Binding Protein-Like 1A (OSBPL1A) Interaction Partners

Human Oxysterol Binding Protein-Like 1A (OSBPL1A) interaction partners

  1. a familial loss-of-function mutation in OSBPL1A affects the first step of the reverse cholesterol transport process and associates with a low HDL (show HSD11B1 Proteins)-C phenotype

  2. ORP1L-VAP (show F10 Proteins) complexes also support transport of LDL-derived cholesterol from endosomes to the endoplasmic reticulum when ORP1L was bound to human adenovirus RIDalpha. RIDalpha-induced lipid trafficking also attenuated proinflammatory signaling by Toll-like receptor 4 (show TLR4 Proteins), which has a central role in adenovirus pathogenesis and is known to be tightly regulated by cholesterol-rich "lipid rafts."

  3. ORP1S is a cytoplasmic sterol sensor, which transports sterols to the nucleus and promotes LXR (show NR1H3 Proteins) regulated trans-activation of apoE (show APOE Proteins).

  4. The study shows that OSBPL1A binds several oxysterols and cholesterol, and characterize a mutant, OSBPL1A Delta560-563, defective in oxysterol bi (show APOA1 Proteins)nding.

  5. Results suggest that the two forms of oxysterol binding protein-related protein-1 (ORP1) are functionally distinct and that ORP1L is involved in control of cellular lipid metabolism

  6. binds to Rab7 (show RAB7B Proteins), modifies its functional cycle, and can interfere with lysosome organization and endocytic membrane trafficking.

  7. OSBPL1A was preferentially expressed from the maternal allele

  8. Results describe how ORP1L contacts VAP (show F10 Proteins) to control Rab7 (show RAB7B Proteins)-RILP (show RILP Proteins)-p150 Glued (show DCTN1 Proteins) and late endosome positioning.

Mouse (Murine) Oxysterol Binding Protein-Like 1A (OSBPL1A) interaction partners

  1. Osbpl1a silencing in macrophage foam cells enhances endosome motility and results in inhibition of [(3)H]cholesterol efflux to apolipoprotein A-I (show APOA1 Proteins).

  2. OSBP (show OSBP Proteins) regulates hepatic TG metabolism and suggest the involvement of OSBP (show OSBP Proteins) in the insulin (show INS Proteins) signaling pathways that control hepatic lipogenesis.

Oxysterol Binding Protein-Like 1A (OSBPL1A) Protein Profile

Protein Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist\; they encode different isoforms.

Gene names and symbols associated with OSBPL1A

  • oxysterol binding protein like 1A (OSBPL1A)
  • oxysterol binding protein-like 1A (Osbpl1a)
  • oxysterol binding protein-like 1A (osbpl1a)
  • oxysterol binding protein-like 1A (OSBPL1A)
  • oxysterol-binding protein-related protein 1 (Tsp_09273)
  • oxysterol-binding protein-related protein 1 (Tsp_03387)
  • oxysterol binding protein like 1A L homeolog (osbpl1a.L)
  • oxysterol binding protein like 1A (osbpl1a)
  • oxysterol binding protein like 1A (Osbpl1a)
  • DKFZp459N1538 protein
  • G430090F17Rik protein
  • Gm753 protein
  • ORP-1 protein
  • ORP1 protein
  • Osbpl1b protein
  • si:dkey-121a11.8 protein

Protein level used designations for OSBPL1A

OSBP-related protein 1 , oxysterol binding protein-like 1B , oxysterol-binding protein-related protein 1 , oxysterol-binding protein-related protein 1 variant 1 , oxysterol-binding protein-related protein 1 variant 2 , ORP-1 , oxysterol-binding protein-like 1A , oxysterol binding protein-like 1A , oxysterol binding protein-like protein 1A , oxysterol-binding protein-related protein 1-like

GENE ID SPECIES
114876 Homo sapiens
64291 Mus musculus
259221 Rattus norvegicus
565503 Danio rerio
100174299 Pongo abelii
10905070 Trichinella spiralis
10909128 Trichinella spiralis
421079 Gallus gallus
468500 Pan troglodytes
480761 Canis lupus familiaris
495678 Xenopus laevis
616555 Bos taurus
677867 Macaca mulatta
100010444 Monodelphis domestica
100127588 Xenopus (Silurana) tropicalis
100356707 Oryctolagus cuniculus
100403124 Callithrix jacchus
100480218 Ailuropoda melanoleuca
100511459 Sus scrofa
100540838 Meleagris gallopavo
100557357 Anolis carolinensis
100600026 Nomascus leucogenys
100717854 Cavia porcellus
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